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Methallylescaline (MAL) is a synthetic psychedelic phenethylamine related to mescaline. Ideal for laboratory research, this compound offers unique visual and stimulatory properties. Buy Methallylescaline online at Chem14.com with discreet shipping to USA, UK, Germany, Australia, and Asia. For research use only.
At Chem14.com, we specialise in providing top-tier research chemicals for sale to the scientific community. As the demand for novel psychoactive substances grows, understanding the chemical and pharmacological profile of compounds like Methallylescaline becomes essential for researchers. This compound, often sought after for its unique structural properties, offers a fascinating subject for forensic and toxicological studies.
🔥 What is Methallylescaline?
Methallylescaline, often abbreviated as MAL, is a synthetic psychedelic substance in the phenethylamine family. It serves as a close structural relative to mescaline but features a methallyloxy group at the 4-position instead of the methoxy found in mescaline. First documented by Alexander Shulgin in his book PiHKAL, this compound produces hallucinogenic effects primarily through action at serotonin receptors. At Chem14.com, we provide high-purity Methallylescaline for scientific investigation.
Methallylescaline (MAL) is a synthetic psychedelic phenethylamine analog of mescaline, known for strong visuals and stimulation, with doses typically 40-65 mg and duration 12-16 hours.
🔬 Chemical and Pharmacological Profile of Methallylescaline
Methallylescaline has the molecular formula C14H21NO3 and a molar mass of 251.32 g/mol. Its CAS number is 207740-41-8. The full chemical name is 4-methallyloxy-3,5-dimethoxyphenethylamine, or more precisely 2-{3,5-dimethoxy-4-[(2-methylprop-2-en-1-yl)oxy]phenyl}ethan-1-amine.
This compound belongs to the scaline class, with modifications that influence its potency and effects compared to natural mescaline. Limited in vitro data shows it binds to serotonin 5-HT2A receptors with moderate affinity (Ki around 550 nM) and acts as a full agonist at certain subtypes (EC50 ~79 nM, efficacy ~85%). These interactions drive its psychoactive profile.
Below is a summary of the key identifiers for Methallylescaline.
| Property | Detail |
|---|---|
| IUPAC Name | 2-(4-Methallyloxy-3,5-dimethoxyphenyl)ethanamine |
| Formula | C13H19NO3 |
| Molecular Weight | 237.29 g/mol |
| CAS Number | 96096-55-8 |
| Purity | ≥98% (HPLC) |
| Form | Powder or HCl Salt |
| Storage | Cool, dry place, away from light |
The CAS number 96096-55-8 is the unique numerical identifier assigned by the Chemical Abstracts Service. This number is crucial for researchers when referencing the compound in scientific literature or ordering from suppliers. You can verify this data through reputable chemical databases like DrugBank or Cayman Chemical.
🧠 How Does Methallylescaline Work? Mechanism of Action Explained
Methallylescaline functions mainly as a serotonin 5-HT2A receptor agonist, similar to other classic psychedelics. Activation of 5-HT2A receptors in the brain leads to altered perception, enhanced visuals, and shifts in cognition. It may also interact with 5-HT2B and 5-HT2C receptors to a lesser degree.
User reports and limited pharmacological studies indicate stimulant-like qualities alongside hallucinogenic ones. The effects stem from increased serotonin signaling, which disrupts normal sensory processing and promotes introspection or euphoria.
🎆 What Are the Effects of Methallylescaline?
Effects of Methallylescaline vary by dose but commonly include:
- Intense open-eye and closed-eye visuals (neon colors, kaleidoscopic patterns, swirling textures)
- Euphoria and empathy
- Enhanced tactile sensations
- Mental stimulation and insight
- Altered time perception
- Possible body load (restlessness, nausea in some cases)
Duration typically spans 12-16 hours, with onset in 20-60 minutes, peak at 3-5 hours, and afterglow lasting several hours. Many compare it to mescaline but note stronger visual components and more physical stimulation.
Bold key point: Visuals often described as “neon theater” or watercolor-like distortions.
⚠️ What Are the Side Effects and Risks of Methallylescaline?
Common side effects reported include:
- Nausea or vomiting (especially during come-up)
- Body load (unease, overstimulation, muscle tension)
- Restlessness or insomnia
- Pupil dilation
- Increased heart rate or blood pressure
Higher doses amplify discomfort. Little formal toxicity data exists, so caution applies in research settings. Avoid combining with other substances.
Side effects of Methallylescaline include nausea, body load, restlessness, and visual overstimulation; risks rise with dose due to limited safety data.
📊 Methallylescaline Dosage Guide Comparison Table
| Dose Level | Amount (mg) | Expected Intensity | Duration (hours) | Common Notes |
|---|---|---|---|---|
| Threshold | 20-30 | Mild perceptual shifts | 8-12 | Subtle energy, light visuals |
| Light | 30-45 | Noticeable euphoria, colors | 10-14 | Good for first exploration |
| Common | 45-60 | Strong visuals, introspection | 12-16 | Typical research range (PiHKAL) |
| Strong | 60-75 | Intense hallucinations | 14-18 | Potential overload, nausea risk |
| Heavy | 75+ | Overwhelming effects | 16+ | Not recommended for most studies |
Note: Doses from user reports and Shulgin’s PiHKAL; always verify in controlled lab contexts.
🌍 Legal Status of Methallylescaline in USA, UK, Germany, Australia
Methallylescaline remains unscheduled in many places but faces restrictions:
- USA: Not explicitly scheduled under the Controlled Substances Act, but potentially prosecutable under the Federal Analogue Act if intended for consumption (analog to mescaline).
- UK: Illegal to produce, supply, or import under the Psychoactive Substances Act 2016.
- Germany: Controlled under the New Psychoactive Substances Act (NpSG) since 2016.
- Australia: Likely falls under analogue provisions or prohibited lists.
Laws change, so check local regulations. At Chem14.com, we sell strictly for research, not human use.
Methallylescaline is unscheduled in USA but analogue risks apply; banned in UK under Psychoactive Substances Act and in Germany via NpSG.
🔬 How to Handle and Store Research Chemicals
Proper handling is paramount when working with potent substances. We adhere to strict safety guidelines, which we detail in our research ethics and safety guidelines.
- Personal Protective Equipment (PPE): Always wear gloves, lab coats, and safety goggles.
- Ventilation: Handle powders in a fume hood to avoid inhalation.
- Storage: Store Methallylescaline in a cool, dark place, preferably in a sealed container to prevent degradation.
- Labelling: Clearly label all vials with the compound name, concentration, and hazard warnings.
Improper handling can lead to contamination or accidental exposure. We urge all researchers to follow institutional protocols. If you are new to handling synthetic cannabinoids or phenethylamines, our guide on how to find reliable research chemical suppliers offers valuable tips on vetting sources.
🌍 Best Place to Order Methallylescaline for Research
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We provide detailed Certificates of Analysis (CoA) for our products. When you buy from Chem14.com, you support ethical scientific inquiry. We believe that access to high-purity reference materials is essential for the advancement of pharmacology.
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What is the CAS Number for Methallylescaline?
The CAS number for Methallylescaline is 96096-55-8. This identifier is used internationally to index the chemical in regulatory and scientific databases.
Is Methallylescaline legal to buy?
In many jurisdictions, it is legal to purchase for “research purposes” or “not for human consumption.” However, it is often controlled if intended for ingestion. Always check your local laws regarding the Psychoactive Substances Act or analogue acts in your country.
How should I store Methallylescaline powder?
Store the powder in an airtight container, protected from light and moisture. A refrigerator is often recommended for long-term storage to maintain stability.
Where can I find reliable research chemical vendors?
Reliable vendors, like Chem14.com, offer transparent testing, secure payment methods, and clear communication. Avoid vendors who do not provide safety data or who make unsubstantiated medical claims.
What are the side effects of Methallylescaline?
While studied in vitro, potential side effects in biological systems may include nausea, vasoconstriction, and anxiety due to its serotonergic activity. For more detailed pharmacological data, refer to resources like Drugs.com.
What is Methallylescaline?
Methallylescaline (MAL) is a synthetic psychedelic phenethylamine, a mescaline analog first described in PiHKAL, producing visuals and stimulation via 5-HT2A agonism.
How long do Methallylescaline effects last?
Effects typically last 12-16 hours, with peak intensity around 3-5 hours after ingestion.
Is Methallylescaline legal in the UK?
No, it falls under the Psychoactive Substances Act 2016, making production, supply, and import illegal.
What are common Methallylescaline visuals like?
Users report neon colors, kaleidoscopic patterns, swirling surfaces, and intense open/closed-eye hallucinations.
Can I buy Methallylescaline in the USA?
Yes for research purposes at Chem14.com, but it may qualify as a mescaline analog under federal law if for consumption.
Does Methallylescaline cause nausea?
Yes, nausea and body load (unease, stimulation) appear common, especially at higher doses.
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Methallylescaline represents a fascinating compound within the phenethylamine class. Its structural similarity to mescaline offers researchers a unique opportunity to study the nuances of receptor binding and psychedelic pharmacology. We at Chem14.com are proud to support the scientific community by providing high-purity materials.
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- Methallylescaline offers unique psychedelic visuals stronger than some mescaline analogs.
- Acts primarily via 5-HT2A receptor agonism.
- Dosage range 40-65 mg; duration 12-16 hours.
- Side effects include nausea and restlessness.
- Legal status varies: research-only in many regions.
- Source high-quality compounds from Chem14.com for your studies.



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