Buy Flubromazepam Online
Flubromazepam is a long-acting designer benzodiazepine, first synthesised in the 1960s but re-emerged in 2012 as a research chemical with an elimination half-life of over 100 hours. Are you looking to buy Flubromazepam online? Chem14 offers lab-tested Flubromazepam for sale with 99.8% purity. Discreet shipping to the UK, USA & Germany
Welcome to Chem14.com, your trusted partner in the world of advanced research chemicals. If you are looking to buy Flubromazepam online, you have arrived at the right place. We understand the precision required in neuropharmacology, which is why we offer rigorously tested Flubromazepam for sale to researchers across the United Kingdom, United States of America, Germany, Australia, and Asia.
In the ever-shifting landscape of novel psychoactive substances, Flubromazepam stands out, not for its potency per milligram compared to some analogues, but for its incredible persistence in biological systems. Sourcing this compound requires a vendor who prioritises data transparency and legal compliance. We built Chem14 on those principles.
Whether you are based in London, New York, Berlin, or Sydney, our mission is to deliver the highest purity materials directly to your laboratory. Let’s explore the intricate details of this fascinating benzodiazepine.
🤔 What is Flubromazepam? Definition and Background
Flubromazepam is a chemical compound belonging to the 1,4-benzodiazepine class. It was first invented in the 1960s but was never developed for medical use by pharmaceutical companies. It remained an obscure molecule until it was identified on the online research chemical market around 2012.
It is structurally described as 7-bromo-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one. The name itself tells a chemical story: “Flu” for the fluorine atom attached to the phenyl ring, and “broma” for the bromine atom at the R7 position of the benzodiazepine core. This specific substitution pattern gives the molecule its unique properties.
Unlike fast-acting medical benzodiazepines, Flubromazepam is characterised by its remarkably long duration, making it a unique tool for specific types of receptor studies. According to the WHO Expert Committee on Drug Dependence, it has no known therapeutic use and is currently under surveillance for potential risks.
🧪 Flubromazepam Chemical Profile and CAS Number
For researchers, accuracy in sourcing starts with the numbers. Here are the vital statistics for Flubromazepam.
| Property | Details |
|---|---|
| IUPAC Name | 7-bromo-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one |
| CAS Number | 2647-50-9 |
| Molecular Formula | C₁₅H₁₀BrFN₂O |
| Molecular Weight | 333.15 g/mol |
| Elimination Half-Life | ~106 hours (range of 100–200 hours reported) |
| Purity (Chem14) | ≥98% (GC/MS validated) |
| Common Research Forms | Powder, Pellet (4mg, 8mg), Infused Papers |
The CAS number 2647-50-9 is your guarantee that you are sourcing the correct molecule. When you order from Chem14, we ensure that every batch aligns with these verified chemical specifications.
How Does Flubromazepam Work? Mechanism of Action
As a benzodiazepine derivative, Flubromazepam exerts its effects by modulating the GABA-A receptor.
Flubromazepam acts as a positive allosteric modulator of GABA-A receptors, enhancing the flow of chloride ions into neurons to induce prolonged central nervous system depression.
Here is the step-by-step breakdown of its pharmacodynamics:
- Receptor Binding: The molecule binds to a specific site on the GABA-A receptor (the benzodiazepine binding site), distinct from the GABA binding site itself.
- GABA Enhancement: This binding increases the receptor’s affinity for its natural neurotransmitter, GABA (gamma-aminobutyric acid) .
- Chloride Influx: When GABA binds, the receptor opens a channel, allowing negatively charged chloride ions to flow into the neuron.
- Hyperpolarisation: This influx of negative charges makes the neuron more resistant to firing (hyperpolarisation), effectively inhibiting neuronal excitability.
Result of Action: This mechanism produces a range of effects in research models, including anxiolytic (anxiety reduction), sedative, muscle relaxant, anticonvulsant, and amnesic properties. The unique aspect of Flubromazepam is its pharmacokinetics; its long half-life (up to 106 hours) means it remains in the system far longer than common benzodiazepines like diazepam.
Legal Status of Flubromazepam in the USA, UK, Germany & Australia
Navigating the legal landscape is critical. At Chem14, we strictly sell Flubromazepam for laboratory and forensic research purposes only, not for human consumption. The legal status varies significantly by region, and we urge our customers to verify their local laws before placing an order.
| Country | Legal Status | Regulatory Context |
|---|---|---|
| United Kingdom (UK) | Class C | Controlled under the Misuse of Drugs Act 1971 (May 2017 amendment). |
| United States (USA) | Schedule I (State-Level) | Not federally scheduled, but controlled in states like Virginia under Schedule I. |
| Germany | Anlage II | Controlled substance under the NpSG; trade is authorised but not prescriptible. |
| Australia | Schedule 9 (S9) | Prohibited substance. Possession or use is illegal without specific permits. |
| Canada | Schedule IV | Controlled under the Controlled Drugs and Substances Act. |
Important Note: According to the ECDD Repository, Flubromazepam is currently under surveillance by the WHO, indicating that international control measures are being actively considered.
💊 Flubromazepam Dosage, Effects, and Duration for Research
When conducting in vitro or in vivo research, understanding the reported dose-response relationship is crucial for safety and experimental design. Data from sources like PsychonautWiki and Tripsitter outline the following parameters observed in animal models and human self-reports (for harm reduction context only).
📏 Reported Dose Guidelines (Oral)
Note: These are not recommendations for human use, but data points for understanding potency in research settings.
- Threshold: 2 mg
- Light: 3 – 5 mg
- Common: 5 – 8 mg
- Strong: 8 – 12 mg
- Heavy: 12 mg +
⏳ Pharmacokinetics
- Onset: 40 – 90 minutes
- Peak Effects: 4 – 6 hours
- Total Duration: 6 – 12 hours (primary effects)
- After-effects (Come down): Up to 24 hours
- Elimination Half-life: 106 hours (approx. 4.4 days). This means it takes over 20 days for the compound to be completely cleared from the body after a single dose.
This prolonged half-life is a key differentiator. It means that in repeated-dose studies, the compound will accumulate significantly, a factor that researchers must account for in their protocols.
🛡️ Safety, Risks, and Side Effects
All research chemicals carry inherent risks. Recent studies have highlighted specific concerns regarding Flubromazepam that go beyond the classic benzodiazepine side effect profile.
⚠️ Adverse Effects Observed in Studies
According to a 2022 study published in Toxicology Research, Flubromazepam demonstrated:
- Cardiotoxicity: In rodent models, it increased RR intervals (the time between heartbeats) and considerably inhibited potassium channels (hERG assay), which are critical for cardiac electrical activity.
- Dependence Potential: The study found that mice exhibited a significant preference for a Flubromazepam-paired compartment, suggesting a high potential for dependence.
⚡ Common Side Effects (Inferred from Class)
As a potent CNS depressant, common adverse reactions observed in animal models and reported in medical literature for similar compounds include:
- Severe sedation and drowsiness
- Ataxia (loss of coordination) and slurred speech
- Respiratory depression (especially when combined with other depressants)
- Anterograde amnesia
- Paradoxical reactions (agitation, aggression) in some subjects
☠️ Dangerous Interactions
Flubromazepam must never be combined with other central nervous system depressants in any non-laboratory setting. This includes:
- Alcohol
- Opioids (This combination is a leading cause of overdose fatalities)
- Barbiturates
- GHB/GBL
🥇 Why Buy Flubromazepam for Sale from Chem14.com?
When you decide to buy Flubromazepam online, you are placing your trust in a supplier. At Chem14, we earn that trust through transparency and quality.
- 🔬 Certified Purity: Our Flubromazepam is tested using GC/MS methodology. We provide Certificates of Analysis (COAs) to verify the ≥98% purity.
- 📦 Discreet Global Shipping: We specialise in secure and discreet packaging to ensure safe delivery to the UK, USA, Germany, Australia, and Asia. Track your order easily via our track-order page.
- ⚖️ Legal Compliance: We are a vendor for legitimate research. We advise all customers to adhere to their local laws and our Legal Disclaimer.
- 🧪 Extensive Catalogue: Beyond Flubromazepam, we offer a wide range of research chemicals including other benzodiazepines , cannabinoids , and stimulants .
“The designer benzodiazepine, flubromazepam, induces reward-enhancing and cardiotoxic effects in rodents.” This recent finding underscores the need for rigorous safety protocols when handling this compound.
📊 Flubromazepam vs. Other Long-Acting Benzodiazepines
How does this compound compare to other research benzodiazepines available in our shop?
| Feature | Flubromazepam (Chem14) | Phenazepam | Diclazepam |
|---|---|---|---|
| CAS Number | 2647-50-9 | 51753-57-2 | 2894-68-0 |
| Half-Life | Very Long (~106 hrs) | Very Long (60+ hrs) | Long (~42 hrs) |
| Primary Structure | Bromine & Fluorine | Bromine & Chlorine | Chlorine only |
| Relative Potency | Moderate | High | Moderate |
| Availability | Buy Flubromazepam | Limited | Buy Diclazepam |
Is Flubromazepam legal in the United States?
Federally, it is not scheduled, but it is an analogue. However, it is a Schedule I controlled substance in states like Virginia. Researchers must check specific state laws.
What is the CAS number for Flubromazepam?
The correct CAS number is 2647-50-9.
How long does Flubromazepam stay in your system?
The elimination half-life is approximately 106 hours. This means it can be detected in biological matrices for several weeks after administration.
Can I buy Flubromazepam online in the UK?
Yes, Chem14 ships to the UK. However, it is a Class C controlled substance and must be handled strictly for research purposes.
What are the risks of Flubromazepam?
Beyond standard sedation and amnesia risks, recent studies indicate potential cardiotoxic effects and a clear signal for dependence liability in animal models.
How is Flubromazepam different from Flubromazolam?
Flubromazepam is a “classic” 1,4-benzodiazepine, while Flubromazolam is a triazolobenzodiazepine (with an additional triazole ring), making it significantly more potent per milligram.
What is the purity of Flubromazepam at Chem14?
We guarantee a purity of ≥98% , validated by independent laboratory analysis.
Where can I find safety data?
We recommend reviewing the Research Ethics & Safety Guidelines on our site before handling any research chemicals.
Does Chem14 ship to Germany?
Yes, we ship to Germany and comply with the NpSG regulations for research compounds.
How should I store Flubromazepam powder?
Store in a cool, dry place, away from light and moisture, preferably in an airtight container at room temperature.
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