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Buy SGT-151 online – What Is SGT-151? (CUMYL-PEGACLONE)

SGT-151, also known as Cumyl-PEGACLONE, is a synthetic cannabinoid that belongs to the gamma-carboline class of compounds. Its CAS number is 2160555-55-3. What makes SGT-151 unique is its chemical structure, combining a cumyl group with a pentyl side chain and a gamma-carboline core. This combination creates a highly potent synthetic cannabinoid that mimics effects similar to natural cannabis but with greater intensity and risks. It was first detected in Germany around 2016 in herbal mixtures marketed as “research chemicals” under the street name “SGT-151” (ResearchGate, Wikipedia). Buy SGT-151 online

• CAS number: 2160555-55-3 (Wikipedia)
• IUPAC name: 2,5-Dihydro-2-(1-methyl-1-phenylethyl)-5-pentyl-1H-pyrido[4,3-b]indol-1-one (UNODC, Wikipedia)
• Molecular formula: C₂₅H₂₈N₂O; Molecular weight: ~372.5 g/mol (gsrs.ncats.nih.gov, ChemicalBook)

SGT-151 belongs to the group of synthetic cannabinoid receptor agonists (UNODC, Wikipedia).

Chemical and Pharmacological Profile – CUMYL-PEGACLONE

SGT-151 CAS Number and Chemical Structure

This compound is not only synthetic but structurally distinct from other cannabinoids, making it a significant focus of analytical and pharmacological research.

SGT-151 stands out for its gamma-carboline core, a structural motif not previously seen in earlier synthetic cannabinoids (Wikipedia).

How Does SGT-151 Work? Mechanism of Action Explained

SGT-151 exerts its effects through binding to the CB1 receptor, a critical component of the endocannabinoid system in the human brain and nervous system. The CB1 receptor influences mood, memory, pain sensation, and appetite. By being a full agonist at this receptor, SGT-151 produces effects much stronger and more unpredictable than natural cannabinoids like THC.

Studies show that SGT-151 has a very high potency with EC50 values in the nanomolar range, indicating strong receptor activation at very low doses. This potent activity is also linked to significant side effects and toxicity risks, making it far less safe than traditional cannabis. The compound also triggers biased signaling pathways that can lead to varied and intense physiological responses. (WHO).

Metabolism & Toxicology

• Extensively metabolised with numerous phase I products, including OH-SGT-151, di-OH-SGT-151, and N-dealkyl SGT-151, which could serve as forensic markers (WHO, PubMed).
• Detected in both blood and urine in forensic cases; metabolites confirmed following surreptitious exposure (PubMed, Oxford Academic).
• Impurities are common in street samples and may increase toxicity risk (ResearchGate).

SGT-151 Effects and Dosage Guide

Although formal clinical trials in humans are lacking, forensic and preclinical findings report:

1. Implicated in fatal outcomes: Found in post-mortem samples, sometimes alongside other substances (WHO, ResearchGate, PubMed).
2. Reported seizures in adolescents following herbal product exposure (WHO).
3. Metabolic complexity and potential for unknown degradation products may elevate risks.

The exact dosage for SGT-151 is currently not well established, largely due to its unpredictable potency and presence mostly in unregulated formulas. Doses vary depending on the product’s purity and the delivery method (typically, herbal blends soaked or sprayed with the compound). Reports advise extreme caution as overdose can lead to serious medical complications, including psychosis and cardiovascular distress.

Explored: Buy SGT-151 Online Safely and Legally

If you are wondering where to buy SGT-151 online or are interested in its availability, platforms like Chem14.com offer access to research-grade SGT-151. It is vital to ensure any purchase is from a reliable research chemical supplier with verified products to avoid counterfeit or dangerously impure substances.

Legal Status

• In the UK, SGT-151 falls under controlled substance regulations, often classified under Class B or covered by the Psychoactive Substances Act.
• In the USA, SGT-151 has temporary Schedule I classification by the DEA since December 2023, making its possession and sale illegal pending permanent classification decisions.
• Other countries, such as Germany and Sweden, have also implemented controls due to their harmful effects and prevalence in illicit markets.

Checking local laws before ordering is essential to avoid legal repercussions.

• SGT-151 is listed in Schedule II of the 1971 Convention on Psychotropic Substances, meaning international controls apply (UNODC).
• Under national frameworks such as Germany’s NpSG or the UK’s PSA, similar compounds often face strict regulation or prohibition (Wikipedia).

Table: Quick Overview

Why Researchers and Forensic Teams Should Know SGT-151

We recognise SGT-151 as a compound that exemplifies modern synthetic cannabinoid design—engineered to avoid legal restrictions, potent at cannabinoid receptors, and demonstrating forensic complexity. Whether you’re monitoring drug trends, conducting analytical studies, or ensuring public safety, understanding SGT-151 remains essential.

Frequently Asked Questions (FAQs) about SGT-151 ❓

What is SGT-151 used for?
SGT-151 is primarily used for research purposes as a synthetic cannabinoid and is not approved for medical or recreational use. It mimics cannabis effects but is much more potent and risky.

Is SGT-151 legal in the UK and USA?
In the UK, SGT-151 is controlled under drug laws, and in the USA, it has a temporary Schedule I status, making it illegal to possess or distribute.

 Where can I buy authentic SGT-151 online?
You can buy authentic SGT-151 online from reputable research chemical vendors such as Chem14, ensuring product purity and safe delivery.

 What are the side effects of SGT-151?
Side effects include anxiety, paranoia, hallucinations, tachycardia, and potential overdose risks. It is crucial to approach this compound with care.

 How is SGT-151 different from natural cannabis?
SGT-151 is a synthetic cannabinoid that acts as a full agonist at CB1 receptors, leading to stronger and often more dangerous effects than natural cannabis, which has partial agonists like THC.

What is SGT-151 used for? Primarily found in research chemical markets and forensic investigations. It is not approved for human use. (ChemicalBook, ResearchGate)

Where was SGT-151 first identified? Detected in Germany in 2016 within herbal blends labelled as SGT-151. (ResearchGate, Wikipedia)

What is the legal status of SGT-151 in the USA and UK? Controlled under international conventions (Schedule II) and similarly regulated in many countries, including the UK and Germany. (UNODC, Wikipedia)

How is SGT-151 detected in samples? By identifying characteristic metabolites like OH-SGT-151 and N-dealkyl SGT-151 in blood or urine via advanced mass spectrometry. (WHO, PubMed)

Key Takeaways

• SGT-151 is a synthetic cannabinoid also known as CUMYL-PEGACLONE, first seen in 2016.
• It acts as a potent full agonist at cannabinoid receptors with high binding affinity.
• Extensive metabolism yields identifiable biomarkers essential for toxicology.
• Associated with serious health risks, including seizures and death.
• It is internationally controlled under Schedule II, and strictly regulated or banned in many regions.

Final Thoughts & Call to Action

At Chem14.com, we value accuracy and transparency. If you’d like to explore cannabinoid profiles or compare SGT-151 with related compounds, feel free to browse our cannabinoids category or our insightful blog. Have thoughts or case studies to share? Let us know—your input enriches the community.

For those interested in expanding their knowledge or exploring related substances, browse other professional research chemicals in our collections of cannabinoids, psychedelics, and more at Chem14.com.

Take control of your research chemical needs. Order SGT-151 now with guaranteed purity and expert support on Chem14.com! Have questions? Our team is ready to assist you.

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