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Buy Flubrotizolam Online . Flubrotizolam is a synthetic thienotriazolodiazepine research chemical that delivers strong sedative and anxiolytic effects in lab settings. At Chem14.com we supply only the highest purity batches for scientific study.
Researchers around the world turn to Flubrotizolam when they need a compound that mirrors classic benzodiazepine activity but with enhanced potency. Developed from a 1978 patent by Boehringer Ingelheim, this molecule features a unique thieno-triazolo structure that sets it apart from standard options. We at Chem14.com stock it because our customers in the USA, UK, Germany, Australia and Asia demand consistent quality for their controlled experiments.
What is Flubrotizolam?
Flubrotizolam (CAS 57801-95-3) is a potent, short-acting thienodiazepine research chemical. It acts as a full agonist at GABA-A receptors, producing pronounced sedative, hypnotic, and anxiolytic effects at microgram doses, making it significantly more potent than traditional benzodiazepines like Diazepam .
The compound carries the CAS number 57801-95-3 and the molecular formula C15H10BrFN4S with a molar mass of 377.24 g/mol. Its systematic name reads 2-bromo-4-(2-fluorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine. These details help labs verify identity through standard analytical methods.
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🔬 What is Flubrotizolam (FANAX) and What is Its Chemical Profile?
Answer Capsule: Flubrotizolam is a novel thienodiazepine, structurally related to Brotizolam but substituted with bromine and fluorine atoms. Its IUPAC name is 4-bromo-7-(2-fluorophenyl)-13-methyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaene .
First emerging in research circles and online markets around 2021, Flubrotizolam represents a new wave of designer benzodiazepines . Unlike prescription drugs, this compound is strictly designated for forensic and laboratory research.
📊 Key Chemical Properties of Flubrotizolam
| Property | Value | Notes for Researchers |
|---|---|---|
| CAS Number | 57801-95-3 | Standard identifier |
| Molecular Formula | C15H10BrFN4S | Confirms structure |
| Molecular Weight | 377.24 g/mol | Useful for molar calculations |
| IUPAC Name | 2-bromo-4-(2-fluorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine | Full systematic reference |
| Common Name | FANAX | Market shorthand |
| Solubility | Low in water, high in DMF/DMSO | Ideal for organic protocols |
| Half-Life | Approximately 5 hours | Short duration suits many assays |
| Typical Research Dose | 0.5 mg | Produces clear measurable effects |
This table centralises data so labs can reference it quickly during planning.
⚗️ Chemical and Pharmacological Profile: Mechanism of Action
To understand the research value of Flubrotizolam, one must look at its interaction with the central nervous system. As a full agonist at the GABA-A receptor, it enhances the effects of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) .
- Receptor Binding: By binding to specific sites on the GABA-A receptor, Flubrotizolam increases the frequency of chloride channel opening. This hyperpolarizes the neuron, making it less excitable.
- Resulting Effects: This mechanism leads to the classic effects associated with potent depressants:
- Sedation & Hypnosis: A powerful suppression of central nervous system activity, useful for studying sleep mechanisms.
- Anxiolysis: Reduction of anxiety in test subjects.
- Muscle Relaxation: Inhibition of motor reflexes.
Its high potency is attributed to the triazole and thiophene rings in its structure, which are common in high-affinity ligands. According to DrugBank, compounds like this are critical for mapping the precise functions of GABA-A receptor subtypes.
🧪 Metabolism and Detection in Biological Samples
Recent studies using human hepatocytes have shed light on how Flubrotizolam is processed. Research published in Metabolites (2024) indicates that Flubrotizolam is metabolized in the liver, primarily by the CYP3A4 enzyme .
- Primary Metabolites: The main metabolic pathways involve hydroxylation, producing 6-hydroxy-flubrotizolam and α-hydroxy-flubrotizolam .
- Detection Windows: These metabolites are the key biomarkers for consumption in forensic casework. Because the parent compound can remain largely unmetabolized for hours, it suggests a low clearance rate and potentially prolonged effects in vivo, which is a critical consideration for toxicological studies .
- Analytical Methods: Detection requires advanced techniques like liquid chromatography-high-resolution tandem mass spectrometry (LC-HRMS/MS) , as standard immunoassays may not detect these novel compounds .
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Our benzodiazepines category also features related compounds such as buy bromazolam online, buy norflurazepam online and buy clonazolam online. Many labs combine these for comparative studies.
Where is Flubrotizolam Legal?
The legal status of Flubrotizolam varies dramatically across the globe. Researchers must verify their local regulations before purchase.
🇬🇧 Is Flubrotizolam Legal in the United Kingdom?
NO. As of 15 January 2025, Flubrotizolam was explicitly added to Part 3 of Schedule 2 to the Misuse of Drugs Act 1971, classifying it as a Class C controlled drug . This makes it illegal to possess, produce, or supply this substance in the UK. Researchers must hold the appropriate Home Office license to work with this compound.
🇺🇸 Is Flubrotizolam Legal in the United States of America?
NO. In the USA, Flubrotizolam is considered a controlled substance analogue. Under the Federal Analogue Act, any substance “substantially similar” to a Schedule I or II drug is treated as a Schedule I substance if intended for human consumption. It is strictly for laboratory use only and is not approved for any medical use.
🇩🇪 Is Flubrotizolam Legal in Germany?
Flubrotizolam falls under the New Psychoactive Substances Act (NpSG) . This act controls substances based on their chemical structure rather than their named effects. As a thienodiazepine, it is covered by this legislation, making its production, trade, and possession for the purpose of human consumption illegal.
🇦🇺 Is Flubrotizolam Legal in Australia?
NO. In Australia, Flubrotizolam is classified under Schedule 9 (Prohibited Substances) of the Poisons Standard. These are substances which may be abused or misused, the manufacture, possession, sale or use of which is prohibited by law except when required for medical or scientific research, or for analytical, teaching or training purposes with approval.
| Country/Region | Legal Status (2025) | Key Regulation | Penalties |
|---|---|---|---|
| United Kingdom | Class C (Controlled) | Misuse of Drugs Act 1971 | Up to 14 years imprisonment |
| United States | Analogue (Schedule I) | Federal Analogue Act | Felony charges, fines |
| Germany | Controlled (NpSG) | New Psychoactive Substances Act | Fines, confiscation |
| Australia | Schedule 9 (Prohibited) | Poisons Standard | Severe penalties, imprisonment |
| Asia (e.g., Japan) | Designated Substance | Pharmaceutical Affairs Law | Arrest, deportation |
Disclaimer: Laws are subject to change. This information is for guidance and does not constitute legal advice. Always consult with a legal expert in your jurisdiction.
⚠️ What Are the Risks, Side Effects, and Safety Protocols?
Given its potency, handling Flubrotizolam requires extreme caution. The safety profile of this compound has not been fully established, but based on its class, significant risks are associated with it.
- Recognised Side Effects: In line with other potent benzodiazepines, adverse effects can include:
- Extreme Sedation and Drowsiness: At higher doses, this can lead to loss of consciousness.
- Cognitive Impairment: Memory loss, confusion, and poor decision-making .
- Respiratory Depression: A severe slowing of breathing, especially when combined with other depressants like alcohol or opioids. This is the primary cause of fatal overdoses .
- Anterograde Amnesia: Inability to form new memories while under the influence.
- Harm Reduction for Researchers:
- Dosage Control: This compound is active in the microgram range. A milligram scale is insufficient for accurate measurement. You must use volumetric dosing or a high-precision analytical balance. A common research dose cited is around 0.5 mg .
- Never Mix: Avoid co-administration with any other CNS depressants in animal models, as this potentiates toxicity .
- Personal Protective Equipment (PPE): Always handle powder with nitrile gloves, safety goggles, and within a fume hood to prevent accidental inhalation or dermal exposure.
- Secure Storage: Store in a cool, dry, dark place at 0-4°C for short term, or -20°C for long term to maintain stability .
💎 How to Buy Flubrotizolam Online Safely: Best Practices
When looking to buy Flubrotizolam, the market can be treacherous. Many vendors sell mislabelled or impure products. At Chem14, we prioritize safety and quality above all.
💊 What Is the Best Flubrotizolam Dosage for Research Purposes?
Laboratory protocols commonly use 0.5 mg of Flubrotizolam as a standard reference dose, with effects appearing below 1 mg total in most test systems.
Exact amounts vary by experimental design, yet vendors consistently supply 0.5 mg units because this range produces measurable results without excess. We recommend starting low and documenting every variable. Our pellets dissolve cleanly for precise volumetric work.
⏰ How Long Does Flubrotizolam Last? Duration and Half-Life Details
Flubrotizolam shows an active window of five to eight hours with a half-life near five hours, making it suitable for short-term research protocols.
This profile supports studies that require clear onset and offset data. Peak activity arrives within 30 to 90 minutes in most models. Researchers in the UK and USA frequently note the predictability compared with longer-acting analogues.
Is Flubrotizolam the same as Flubromazolam?
No. While both are potent designer benzodiazepines, they are chemically distinct. Flubrotizolam is a thienodiazepine (containing a sulfur atom in its ring structure) and is an analogue of Brotizolam. Flubromazolam is a traditional benzodiazepine analogue of Flubromazepam. Their metabolic pathways and potency can differ.
How long does Flubrotizolam stay in your system?
Detection windows depend on the biological matrix and the assay used. The parent compound may be detectable for a shorter period, but its hydroxylated metabolites (6-hydroxy- and α-hydroxy-flubrotizolam) are the recommended biomarkers and can be detected for several days post-administration using LC-HRMS/MS .
Can I buy Flubrotizolam for human consumption?
Absolutely not. At Chem14, all our products, including Flubrotizolam, are strictly for research and forensic use only. They are not for human consumption, in vivo testing, or veterinary use. Purchasers must be over 18 and agree to our terms of service.
What are the best alternatives to Flubrotizolam for GABA research?
Depending on your research goals, alternatives might include Etizolam (a thienodiazepine with a shorter half-life), Clonazolam (a high-potency triazolobenzodiazepine), or Flubromazolam (for studies requiring a very long half-life). You can explore our full range of benzodiazepines to find the right tool for your specific research.
Is there a risk of dependence in research models?
Yes. Like all full agonists at the GABA-A receptor, repeated administration in animal models can lead to tolerance, physical dependence, and severe withdrawal symptoms upon cessation. This is a critical aspect of the pharmacological profile that researchers must account for when designing long-term studies.
🔄 Flubrotizolam vs Brotizolam
Brotizolam serves as the closest pharmaceutical cousin yet Flubrotizolam demonstrates noticeably higher potency in side-by-side tests. Both share the thieno core, but the fluorine substitution in our compound sharpens receptor affinity. Duration stays similar while onset feels crisper with the research version. Many teams at Chem14.com customers order both for direct parallel studies.
🛡️ Research Ethics and Safety Guidelines at Chem14.com
We follow strict research ethics and safety guidelines. Every product page links to our full research ethics and safety guidelines. We ship with tamper-evident packaging and provide tracking to New York, London and Sydney alike. Our return policy protects legitimate scientific buyers.
What is Flubrotizolam used for in research?
Scientists study its sedative and anxiolytic profile in GABA receptor assays and behavioural models. We supply it strictly for these laboratory purposes.
Can I buy Flubrotizolam in the UK or USA?
Yes, where local regulations permit research use. We ship to qualified buyers in both countries with full documentation. Check our how to order page.
How does Flubrotizolam compare to other benzodiazepines we sell?
It sits between etizolam and clonazolam in potency while keeping a short duration. Browse our full benzodiazepines selection for direct alternatives.
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We accept major cards and crypto with express shipping to the USA, UK, Germany, Australia and Asia. Track every package from our track order portal.
Is Flubrotizolam the same as Flubromazolam?
No. Flubrotizolam features the thieno ring while Flubromazolam uses a benzo-triazolo structure. They differ in legal status and potency profile.
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