Buy 5F-MDA-19 online
The landscape of synthetic cannabinoids is constantly shifting, offering researchers new compounds to analyse and understand. Among these, 5F-MDA-19 has emerged as a substance of significant interest within the scientific community. As a leading supplier, we at Chem14.com believe in providing thorough, accurate data to support safe and effective research. Buy 5F-MDA-19 online, covering its chemical structure, mechanism of action, and legal standing across the globe.
What is 5F-MDA-19?
5F-MDA-19 is a potent synthetic cannabinoid that acts as a full agonist at both CB1 and CB2 receptors. Belonging to the indazole-3-carboxamide family, 5F-MDA-19 is structurally related to other well-known research chemicals. It is often compared to its parent compound, MDA-19, but with a distinct fluorine substitution on the pentyl chain. This slight modification often drastically alters the binding affinity and metabolic stability of the molecule. Researchers value this compound for its ability to bind selectively to cannabinoid receptors, making it a vital tool in studying the endocannabinoid system.
🧬 Chemical Profile and CAS Number
Understanding the molecular makeup is essential for any laboratory analysis. The compound is formally recognized by its CAS number, 1715016-74-2.
Below is a detailed breakdown of its chemical specifications:
| Property | Details |
|---|---|
| Chemical Name | Methyl 2-[[1-(5-fluoropentyl)-1H-indazol-3-yl]carbonylamino]-3,3-dimethylbutanoate |
| Common Name | 5F-MDA-19, 5FMDA19 |
| CAS Number | 1715016-74-2 |
| Formula | C20H28FN3O3 |
| Molecular Weight | ~377.46 g/mol |
| Purity | ≥98% (standard for research) |
| Appearance | White to off-white powder or crystalline solid |
The presence of the fluorine atom at the terminal end of the pentyl chain is a critical structural feature. This addition is a common strategy in medicinal chemistry to increase lipophilicity and metabolic stability, allowing the compound to remain active in the system for longer periods. When you decide to buy 5F-MDA-19 online, verifying these specifications against the Certificate of Analysis (COA) is a step we highly recommend.
How Does 5F-MDA-19 Work? Mechanism of Action
To truly appreciate the research potential of 5F-MDA-19, one must look at its pharmacodynamics.
Interaction with CB1 and CB2 Receptors
Like many compounds in the indazole class, 5F-MDA-19 functions primarily as an agonist. This means it binds to and activates the cannabinoid receptors, specifically CB1 and CB2.
- CB1 Receptors: Primarily located in the central nervous system. Activation here is typically associated with psychoactive effects, including alterations in perception, mood, and memory.
- CB2 Receptors: Mostly found in the immune system and peripheral tissues. Agonism here is often linked to anti-inflammatory and immunomodulatory effects.
According to data available on pharmacological databases like DrugBank, compounds within this class often exhibit higher binding affinity for CB1 receptors compared to natural THC. This potent receptor activation is what makes synthetic cannabinoids like 5F-MDA-19 a subject of intense study for their therapeutic potential and their risk profile.
Metabolic Pathways
Once ingested or administered in a research setting, the body begins to process the compound. The fluorine atom mentioned earlier helps the molecule resist rapid degradation by liver enzymes. This metabolic stability means the effects, or the observable reactions in a test subject, can be more prolonged and intense compared to non-fluorinated analogues. Researchers studying pharmacokinetics find this aspect particularly useful when analysing how structural changes impact drug half-life.
📊 Potential Effects and Side Effects
While our primary focus at Chem14 is supplying chemicals for forensic and laboratory analysis, understanding the physiological effects is crucial for handling safety protocols.
Reported Physiological Effects
Based on anecdotal reports found on platforms like PsychonautWiki and TripSitter, the effects of 5F-MDA-19 are consistent with potent cannabinoid agonists.
- Analgesia: Reduction in pain sensation.
- Sedation: Feelings of sleepiness or relaxation.
- Euphoria: Intense feelings of well-being.
- Appetite Stimulation: Increased hunger, colloquially known as “the munchies.”
Adverse Reactions and Risks
The high potency of 5F-MDA-19 brings a corresponding risk of adverse side effects, especially at higher doses.
- Tachycardia: Rapid heart rate, which can be dangerous for individuals with underlying cardiovascular conditions.
- Anxiety and Paranoia: Unlike the relaxing effects of natural cannabis, synthetic analogues can induce severe panic attacks.
- Nausea and Vomiting: Particularly in cases of overdose.
- Cognitive Impairment: Short-term memory loss and confusion.
We strongly advise all researchers to adhere to strict safety guidelines. Using appropriate personal protective equipment (PPE) and working in a well-ventilated laboratory environment is non-negotiable. You can read more about our safety protocols on our research ethics and safety guidelines page.
⚖️ Legal Status and Regulations
Navigating the legal landscape of research chemicals is complex. The status of 5F-MDA-19 varies significantly depending on your jurisdiction.
United Kingdom
In the UK, the Psychoactive Substances Act 2016 is the primary legislation controlling synthetic cannabinoids. Generally, substances intended for human consumption that affect mental functioning are illegal. However, exemptions exist for legitimate research. As a reliable research chemical supplier, we ensure our products are strictly sold for laboratory and forensic analysis purposes, not for human ingestion.
United States of America
In the USA, the situation is governed by the Federal Analogue Act. This act allows for the prosecution of compounds that are “substantially similar” to Schedule I controlled substances if intended for human use. Many states have also banned specific synthetic cannabinoids explicitly. Researchers in the USA must check their state laws before attempting to order 5F-MDA-19.
Germany and Europe
Germany typically controls new psychoactive substances under the NpSG (New Psychoactive Substances Act). 5F-MDA-19 may be controlled if it is listed in the annexes of the legislation. Across the rest of Europe, regulations vary, with some countries banning entire classes of synthetic cannabinoids.
Asia and Australia
Countries like China, a major producer of precursor chemicals, have tightened regulations on synthetic cannabinoids in recent years. Australia classifies many analogues under Schedule 9 of the Poisons Standard, prohibiting possession except with specific licenses.
“Always verify the current legal status in your region before purchasing. Laws change frequently, and ignorance is not a defense.”
💎 Where to Buy 5F-MDA-19 Online Safely?
Finding a trustworthy vendor is the most challenging aspect of sourcing research materials. The market is flooded with low-quality products and scams.
Why Choose Chem14?
We position ourselves as a premier research chemical vendor in the USA and beyond. Here is why researchers choose us:
- Verified Purity: Every batch of 5F-MDA-19 undergoes rigorous testing. We provide COAs to verify the molecular structure and purity levels.
- Discreet Packaging: We understand the sensitive nature of these materials. Our packaging is discreet and secure, ensuring privacy for our clients in the UK, USA, Germany, and Australia.
- Secure Payment Gateways: We utilize encrypted payment processing to protect your financial data.
- Customer Support: Our team is knowledgeable about our product catalogue. If you need help deciding between 5F-MDA-19 and other cannabinoids like SGT-78 or JWH-018, we are here to assist.
How to Place an Order
Ordering from us is straightforward. Simply visit our shop, select the desired quantity, and proceed to checkout. We offer various shipping options to ensure your buy research chemicals online experience is seamless. If you are looking for other categories, we also stock benzodiazepines, stimulants, and psychedelics.
🔬 Comparative Analysis: 5F-MDA-19 vs. Other Cannabinoids
To better understand where 5F-MDA-19 fits in the current research landscape, it helps to compare it with other popular substances.
| Compound | Structure | Potency | Duration | Notes |
|---|---|---|---|---|
| 5F-MDA-19 | Indazole-3-carboxamide | High | Long | Known for strong CB1 affinity and metabolic stability due to fluorination. |
| MDA-19 | Indazole-3-carboxamide | Moderate | Medium | The non-fluorinated parent compound; generally less potent. |
| 5F-ADB | Indazole-3-carboxamide | Very High | Long | Notorious for high toxicity and severe side effects; strictly controlled. |
| JWH-018 | Naphthoylindole | Moderate | Medium | One of the earliest synthetic cannabinoids; widely banned globally. |
| SGT-78 | Indazole-3-carboxamide | High | Long | Structurally similar to 5F-ADB, potent and long-lasting. |
This table illustrates the “arms race” in synthetic drug design, where chemists modify structures to evade laws or increase potency. 5F-MDA-19 sits in the higher tier of potency, requiring researchers to handle it with extreme care.
💡 Key Takeaways for Researchers
- Safety First: The high potency of 5F-MDA-19 necessitates the use of appropriate safety gear, including gloves, goggles, and fume hoods.
- Legal Compliance: Always check local laws. The responsibility for legal compliance lies solely with the purchaser.
- Quality Matters: Impure samples can skew research results and create unpredictable hazards. Always source from verified suppliers like Chem14.
- Start Small: In laboratory settings, begin with the smallest possible effective dose to gauge the reactivity of the compound.
❓ Frequently Asked Questions (FAQs)
We have compiled a list of the most common questions researchers ask about 5F-MDA-19.
What is the CAS number for 5F-MDA-19?
The CAS number for 5F-MDA-19 is 1715016-74-2. This unique numerical identifier is essential for ordering and cataloguing the chemical in laboratory inventories.
Is 5F-MDA-19 legal in the United Kingdom?
In the UK, 5F-MDA-19 is likely considered a psychoactive substance under the Psychoactive Substances Act 2016. It is illegal to supply it for human consumption. However, it may be purchased for legitimate forensic or research purposes if the vendor holds the necessary licenses.
How should I store 5F-MDA-19?
To maintain stability and purity, store 5F-MDA-19 in a cool, dry place away from direct sunlight. Ideally, keep it in a sealed container at temperatures between -20°C and room temperature. This prevents degradation of the chemical structure over time.
What are the risks of handling 5F-MDA-19?
The primary risks involve accidental exposure through inhalation or skin contact. Due to its high potency, even small amounts absorbed through the skin can cause physiological effects. Always wear nitrile gloves and a lab coat.
Can I buy 5F-MDA-19 with credit card?
Yes, at Chem14.com, we accept various payment methods including credit cards and cryptocurrency, ensuring a secure transaction process for our global clientele.
Is 5F-MDA-19 “safe”?
No. Synthetic cannabinoids pose unpredictable health risks. Even small errors in dosing or synthesis can be life-threatening.
How does it compare to natural weed?
It’s far more potent and less studied. Natural cannabis has decades of research; 5F-MDA-19 is a newcomer with unknown long-term effects.
Can I use it for medical purposes?
There’s zero clinical evidence supporting therapeutic use. Stick to FDA-approved options.
4. What if I encounter a bad batch?
Stop immediately. Seek medical help if you experience chest pain, seizures, or severe psychological distress.
5. Is it detectable in drug tests?
Yes. Standard urine tests may not catch it, but specialized panels (like those for NPS) can. Assume you’ll test positive.
🔚 Conclusion
5F-MDA-19 represents a fascinating yet complex chapter in the ongoing study of synthetic cannabinoids. Its potent receptor affinity and structural nuances offer valuable insights for pharmacological research. However, this same potency demands respect and rigorous safety protocols.
Whether you are in the UK, USA, Germany, or Australia, Chem14 is your trusted partner for acquiring high-quality research chemicals. We bridge the gap between supply and science, ensuring you have the materials you need to advance your work.
Ready to advance your research? Visit our product page to check availability and pricing. For any further inquiries, do not hesitate to contact us. We are here to support your scientific journey.
Disclaimer: All products sold by Chem14.com are strictly for research and forensic purposes only. They are not intended for human consumption or in vivo testing. Purchasers must be over 18 years of age and comply with all local laws and regulations.




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