Buy 5-Bromo-DMT Online | What is 5-Bromo-DMT? – Chem14.com
Discover 5-Bromo-DMT (Sea DMT): the intriguing brominated tryptamine from marine sponges with potential antidepressant effects and low hallucinogenic risk. Buy research-grade 5-Bromo-DMT online safely at Chem14.com for lab studies! Buy 5-Bromo-DMT Online | What is 5-Bromo-DMT? – Pure Research Chemicals for sale
What is 5-Bromo-DMT?
5-Bromo-DMT is a brominated derivative of DMT, a psychedelic tryptamine alkaloid found in marine sponges, known for its potential non-hallucinogenic psychoplastogenic and antidepressant-like properties in preclinical models.
At Chem14.com, we provide 5-Bromo-DMT as a research chemical for laboratory purposes. This compound, often nicknamed Sea DMT or SpongeBob DMT, occurs naturally in sponges such as Smenospongia aurea, Smenospongia echina, and Verongula rigida. Unlike classic DMT, which produces intense hallucinations, 5-Bromo-DMT shows distinct profiles in studies, including activation of serotonin receptors without strong hallucinogenic responses in animal models.
Researchers value 5-Bromo-DMT for exploring modifications to the tryptamine structure. The bromine at the 5-position alters binding affinities and functional outcomes compared to parent DMT.
What is the CAS Number and Chemical Profile of 5-Bromo-DMT?
5-Bromo-DMT has CAS number 17274-65-6, molecular formula C12H15BrN2, and molar mass 267.17 g/mol – a key tryptamine for advanced neuropharmacology studies.
The chemical structure features an indole ring with bromine at position 5 and a dimethylaminoethyl side chain at position 3. PubChem lists it as 5-Bromo-N,N-dimethyltryptamine (CID 360252). It appears as a crystalline solid suitable for analytical work. Suppliers like Cayman Chemical offer it as a reference standard.
Key Chemical Properties Table
| Property | Value | Notes |
|---|---|---|
| CAS Number | 17274-65-6 | Standard identifier |
| Molecular Formula | C12H15BrN2 | Brominated tryptamine |
| Molar Mass | 267.17 g/mol | Precise calculation |
| SMILES | CN(C)CCc1c[nH]c2ccc(Br)cc12 | Canonical string |
| Appearance | Crystalline solid | Typical for research-grade |
| Solubility (examples) | DMF: 10 mg/ml, DMSO: 5 mg/ml | From supplier data |
| Synonyms | 5-Br-DMT, Sea DMT | Common research names |
Table 1: This profile supports precise handling in controlled environments.
How Does 5-Bromo-DMT Work? Mechanism of Action Explained
5-Bromo-DMT activates 5-HT2A receptors but shows low hallucinogenic potential, promoting neuroplasticity and antidepressant effects without inducing head twitch response in mice.
Recent research highlights 5-Bromo-DMT as a psychoplastogen – a compound inducing rapid neuronal changes. It binds serotonin receptors, particularly 5-HT2AR, yet fails to trigger classic hallucinogenic markers like head twitch in rodents. This suggests biased signaling pathways favoring neuroplasticity over perceptual disruption.
Studies indicate potential antidepressant properties, with sedative effects and reduced locomotor activity observed. Unlike 5-MeO-DMT or standard DMT, which strongly agonize multiple serotonin sites leading to intense experiences, 5-Bromo-DMT offers a milder profile.
For more on halogenated tryptamines, see the study on neuropharmacology of halogenated DMT analogs.
What Are the Effects and Potential Side Effects of 5-Bromo-DMT?
Preclinical data show 5-Bromo-DMT produces sedative effects, reduced locomotor activity, and antidepressant-like actions with minimal hallucinogenic side effects in models.
Human data remains limited due to its research-only status. Animal studies report sedative outcomes and locomotor suppression. No strong visual or auditory hallucinations appear, differing from parent DMT.
Potential side effects in research contexts include mild cardiovascular changes or serotonin-related responses, though less pronounced than classic psychedelics. Always adhere to safety protocols.
Comparative Analysis: DMT vs 5-Bromo-DMT 📉
To highlight the unique nature of this compound, we have prepared a comparison table. This helps researchers decide which compound suits their specific experimental needs.
| Feature | DMT (N,N-Dimethyltryptamine) | 5-Bromo-DMT (5-bromo-N,N-dimethyltryptamine) |
|---|---|---|
| Chemical Class | Tryptamine | Brominated Tryptamine |
| Molecular Weight | 188.27 g/mol | 267.16 g/mol |
| Substituent | None | Bromine atom at position 5 |
| Metabolic Stability | Low (rapidly metabolized by MAO) | Moderate to High (potentially MAO resistant) |
| Duration of Action | Short (15-60 mins) | Theoretically Longer |
| Legal Status (USA) | Schedule I | Schedule I (Analogue Act) |
| Primary Research Use | Neuroscience, psychedelic therapy | Receptor binding studies, SAR analysis |
Table 2: Comparison of structural and pharmacological properties.
Is 5-Bromo-DMT Legal? Status in UK, USA, Germany, Australia
5-Bromo-DMT holds Class A status in the UK and remains illegal in Singapore; in the USA, it falls under analog provisions for research but not explicitly scheduled.
In the United Kingdom, 5-Bromo-DMT classifies as Class A under the Misuse of Drugs Act due to structural similarity to controlled tryptamines. Singapore prohibits it outright.
In the United States, it lacks explicit Schedule I listing but may trigger the Federal Analogue Act if intended for consumption. Research use with proper licensing remains permissible.
Germany, Australia, and many Asian countries regulate it under analog laws or novel psychoactive substance controls. Always verify local regulations before ordering.
At Chem14.com, we supply strictly for legitimate scientific research in compliant jurisdictions.
Where Can I Buy 5-bromo-DMT Online? 🛒
We supply premium grade 5-bromo-DMT for legitimate laboratory research. Our products undergo rigorous third-party testing to ensure purity.
Finding a reliable vendor is the most challenging step for researchers. The market is flooded with low-quality products. Chem14.com stands out as a trusted partner for scientists and institutions. When you buy 5-bromo-DMT from us, you are guaranteed:
Where to Buy 5-Bromo-DMT Online Safely in USA, UK, Europe?
Chem14.com offers pure 5-Bromo-DMT for sale as a research chemical with discreet shipping to qualified buyers in USA, UK, Germany, Australia, and select Asian regions.
We prioritize quality and compliance. Browse our tryptamines for sale category for related compounds like 4-HO-MiPT, 5-MeO-DiPT, or proscaline.
If you are ready to add this compound to your catalogue, visit our shop or browse our extensive tryptamines for sale category. We also stock a wide range of other products such as synthetic cannabinoids and dissociatives.
Frequently Asked Questions (FAQs) About 5-Bromo-DMT
What exactly makes 5-Bromo-DMT different from regular DMT?
The bromine substitution at position 5 reduces hallucinogenic intensity while preserving receptor activation, leading to psychoplastogenic rather than full psychedelic effects.
Can I use 5-Bromo-DMT for human consumption?
No. It remains strictly for research and forensic applications only. Human use lacks safety data and violates laws in most regions.
Does 5-Bromo-DMT occur naturally?
Yes, in marine sponges like Smenospongia aurea and Verongula rigida, earning nicknames like Sea DMT.
What are the main research interests in 5-Bromo-DMT?
Scientists examine its antidepressant potential, low hallucinogenic profile, and role in neuroplasticity pathways.
Is 5-Bromo-DMT available in other forms like pellets or sprays?
Currently offered as powder for analytical work; check our psychedelics category for similar tryptamines.
How does 5-Bromo-DMT compare to 5,6-Dibromo-DMT?
Both show promise, but 5,6-Dibromo-DMT displays stronger antidepressant actions in some models, while 5-Bromo-DMT leans sedative.
What is the CAS number for 5-bromo-DMT?
The CAS number for 5-bromo-DMT is 69538-60-5. This unique numerical identifier is used by chemists and researchers to distinguish this specific chemical substance from others.
Is 5-bromo-DMT legal to buy in the UK?
In the UK, the substance is likely controlled under the Psychoactive Substances Act 2016. It is illegal to supply it for human consumption. However, it may be possessed for legitimate research purposes under specific exemptions, though this is legally complex. You should verify current legislation.
How does 5-bromo-DMT differ from 5-MeO-DMT?
While both are substituted tryptamines, 5-MeO-DMT contains a methoxy group, whereas 5-bromo-DMT contains a bromine atom. The bromine atom is much larger and heavier, which significantly changes the molecule’s shape and its interaction with receptors. 5-bromo-DMT is generally considered more stable metabolically.
Can I use 5-bromo-DMT for human consumption?
No. 5-bromo-DMT is strictly sold for laboratory research purposes only. It is not approved for human consumption. The toxicological effects are not fully understood, and ingestion poses serious health risks.
Where can I find reliable research chemical vendors?
Reliable vendors prioritize purity, testing, and customer education. Chem14.com is a leading supplier. We recommend reading reviews and checking for third-party lab reports before you buy research chemicals online. Our about page details our quality control measures.What is the molecular formula of 5-bromo-DMT?
The molecular formula is C12H15BrN2. This indicates the presence of 12 carbon atoms, 15 hydrogen atoms, one bromine atom, and two nitrogen atoms.
How should 5-bromo-DMT be stored?
Like most tryptamines, it should be stored in a cool, dry place, away from direct sunlight. Ideally, it should be kept at -20°C for long-term storage to maintain stability and prevent degradation.
Do you ship 5-bromo-DMT to the USA?
We ship to various locations, but customers in the USA must be aware of the Federal Analogue Act. We comply with all export regulations, but the importer is responsible for ensuring the legality of the substance upon entry into their country. Please check our FAQ for shipping policies.
What is the purity level of Chem14’s 5-bromo-DMT?
We typically supply our compounds at a purity level of 98% or higher. Certificates of Analysis (COA) are available upon request to verify the chemical composition.
Are there other similar tryptamines available?
Yes, we carry a vast selection of tryptamines. You can browse our full catalogue of psychedelic research chemicals for sale to find compounds that may suit your research, such as 4-AcO-DMT or 5-MeO-DMT derivatives where legal.
Key Takeaways
- 5-Bromo-DMT (CAS 17274-65-6) represents a fascinating halogenated tryptamine with marine origins.
- It activates 5-HT2AR without strong hallucinations.
- Preclinical work suggests antidepressant and sedative properties.
- Legal restrictions apply in UK (Class A), USA (analog risks), and elsewhere.
- Purchase only for research from trusted vendors like Chem14.com.
We encourage responsible research. Share your thoughts on tryptamine derivatives in the comments or explore our blog for more insights.
Disclaimer: All products sold by Chem14.com are strictly for research and forensic purposes only. They are not intended for human consumption or veterinary use. The information provided in this article is for educational purposes only.



