Buy 4-AcO-MET online UK
At Chem14.com, we dedicate ourselves to providing the scientific community with high-grade novel compounds. As interest in synthetic tryptamines grows, researchers seek reliable sources to buy research chemicals online for legitimate study. One such compound gaining traction in analytical laboratories is 4-AcO-MET. This substance, known formally as 4-acetoxy-N-methyl-N-ethyltryptamine, offers a unique profile for studying the interactions between synthetic agents and the serotonin system.
Our commitment lies in offering products that meet rigorous standards. We ensure that when you order 4-AcO-MET from us, you receive a material suitable for advanced chemical analysis. This guide will provide a deep dive into the chemical nature, pharmacological profile, and research potential of this molecule.
🔬 What Is 4-AcO-MET? Definition, CAS Number, and Chemical Profile
4-AcO-MET Overview
| Property | Details |
|---|---|
| Chemical Name | 4-Acetoxy-N-methyl-N-ethyltryptamine |
| CAS Number | 2748591-02-6) |
| Class | Synthetic Tryptamine, Psilocin Prodrug |
| Metabolite | 4-HO-MET (Metocin) |
| Dosage Range (Oral) | 5–40 mg |
| Duration | 4–10 hours |
| Legal Status (UK) | Class A (controlled as an ester of 4-HO-MET) |
| Legal Status (USA) | Unscheduled (analogue status possible) |
| Legal Status (EU) | Varies; legal for research in some countries (e.g., Ireland, Italy, Spain) |
4-AcO-MET, also known as Metacetin or Azomet, is a novel psychedelic compound of the tryptamine family. It is the acetate ester of 4-HO-MET, a close relative of psilocin (the active metabolite of psilocybin mushrooms). Like 4-AcO-DMT, it is believed to act as a prodrug, rapidly converting to 4-HO-MET in the body, producing effects similar to psilocybin but with unique nuances in duration and intensity.
4-AcO-MET Mechanism of Action: How It Works in the Brain
4-AcO-MET primarily exerts its effects by binding to serotonin receptors, particularly the 5-HT2A receptor, which is responsible for the hallucinogenic and mood-altering properties of classic psychedelics. Once ingested, it is hydrolyzed into 4-HO-MET by serum esterases, mirroring the metabolic pathway of psilocybin to psilocin.
Key Pharmacological Actions:
- 5-HT2A Agonism: Drives visual hallucinations, emotional shifts, and cognitive effects.
- 5-HT1A/2C Interaction: May contribute to mood elevation and introspective experiences.
- Prodrug Conversion: Rapid deacetylation ensures a smooth onset, often described as less nauseating than psilocybin mushrooms.
4-AcO-MET Dosage Guide: Safe and Effective Use
4-AcO-MET Dosage Guidelines
| Dose Range (mg) | Effects | Duration |
|---|---|---|
| 5–10 | Threshold; mild visual enhancements, subtle mood lift | 4–6 hours |
| 10–20 | Moderate; vivid visuals, emotional introspection, enhanced sensory perception | 6–8 hours |
| 20–30 | Strong; profound hallucinations, ego dissolution, mystical experiences | 8–10 hours |
| 30–40 | Heavy; intense visuals, potential overwhelming cognitive effects (not recommended for beginners) | 8–12 hours |
Note: Always start with a low dose (5–10 mg) to assess sensitivity. Effects typically peak at 2–3 hours and gradually taper off.
4-AcO-MET Side Effects and Safety Profile
While 4-AcO-MET is generally considered low in toxicity, responsible use is critical. Reported side effects include:
- Physical: Nausea (less than psilocybin), muscle tension, pupil dilation, yawning, and mild sedation.
- Psychological: Anxiety, paranoia, or confusion (especially in high doses or unfavorable settings).
- Cardiovascular: Rare reports of increased heart rate or blood pressure; avoid if you have pre-existing conditions.
Harm Reduction Tips:
- Set and Setting: Use in a calm, safe environment with a trusted trip sitter.
- Avoid Mixing: Do not combine with other serotonergic substances (e.g., SSRIs, MAOIs) due to serotonin syndrome risk.
- Test Kits: Always verify purity with a reagent test kit before use.
4-AcO-MET Legal Status: UK, USA, Germany, Australia, and Asia (2026 Update)
The legal status of 4-AcO-MET varies significantly across different jurisdictions. Researchers must understand the laws in their specific region.
- United Kingdom: In the UK, this substance is likely to be considered a Class A drug under the Psychoactive Substances Act 2016 due to its psychoactive properties.
- United States: In the USA, it may be considered a Schedule I controlled substance analogue under the Federal Analogue Act if intended for human consumption.
- Germany: Germany controls this substance under the NpSG (New Psychoactive Substances Act).
We urge all customers to check their local laws before purchasing. You can find more information about regulated substances on Wikipedia. At Chem14.com, we comply with all export regulations and will not ship to countries where the substance is strictly prohibited.
| Country/Region | Legal Status | Notes |
|---|---|---|
| United Kingdom | Class A (illegal to possess, supply, or produce) | Controlled as an ester of 4-HO-MET. |
| United States | Unscheduled (legal grey area; may be considered a psilocin analogue under the Federal Analogue Act) | Not explicitly banned, but risks exist. |
| Germany | Controlled (under NpSG) | Illegal for human consumption; research use may be permitted. |
| Australia | Schedule 9 (prohibited) | Considered an analogue of psilocybin. |
| Asia | Varies (strictly illegal in most countries; research use rare) | Check local laws before ordering. |
| EU (Select) | Legal for research (e.g., Ireland, Italy, Spain) | Sold as a research chemical. |
Important: Always check local regulations before purchasing. Chem14.com does not ship to countries where 4-AcO-MET is prohibited.
4-AcO-MET vs. Psilocybin: Key Differences
| Feature | 4-AcO-MET | Psilocybin (Magic Mushrooms) |
|---|---|---|
| Onset | 30–60 minutes | 30–90 minutes |
| Duration | 4–10 hours | 4–6 hours |
| Nausea | Less pronounced | Often significant |
| Visuals | Bright, neon-like, DMT-esque | Earthy, organic |
| Body Load | Mild to moderate | Often heavier |
| Legal Risk | Varies (grey area in many regions) | Illegal in most countries |
User reports suggest 4-AcO-MET offers a cleaner, more visual experience with less body discomfort, making it a popular choice for research and personal exploration.
Where to Buy 4-AcO-MET Online Safely in 2026
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Is 4-AcO-MET the same as psilocybin?
No, but it is a prodrug of 4-HO-MET, which is structurally and functionally similar to psilocin (the active metabolite of psilocybin). Effects are comparable but often described as smoother and more visual.
What is the best 4-AcO-MET dosage for beginners?
Start with 5–10 mg to gauge sensitivity. Never exceed 20 mg for your first experience.
How long does 4-AcO-MET last?
Effects typically last 4–10 hours, with a peak at 2–3 hours post-ingestion.
Is 4-AcO-MET legal in the USA?
It is unscheduled but may fall under the Federal Analogue Act if intended for human consumption. Always check state laws.
Can I microdose 4-AcO-MET?
Yes, but doses should be sub-perceptual (1–3 mg). Microdosing may enhance creativity and focus, but long-term effects are not well-studied.
Is 4-AcO-MET legal in the UK?
In the UK, 4-AcO-MET is generally controlled under the Psychoactive Substances Act. It is illegal to supply or produce it for human consumption. Possession for research purposes in a licensed laboratory may be permitted, but strict regulations apply.
What is the CAS number for 4-AcO-MET?
The CAS number for 4-AcO-MET is 92292-84-7. This unique numerical identifier is used by chemists and researchers to index the chemical substance in databases.
How should I store 4-AcO-MET powder?
We recommend storing the powder in a cool, dry place, ideally in a refrigerator. Keeping it in an airtight container and under an inert gas like argon will prevent oxidation and degradation over time.
Can I buy 4-AcO-MET with Bitcoin?
Yes, at Chem14.com we accept various payment methods including cryptocurrencies to ensure privacy and security for our customers. You can easily buy research chemicals online using your preferred payment option.
Where can I find the best 4-AcO-MET for sale?
The best 4-AcO-MET for sale is found through vendors who provide third-party lab testing. We ensure that every batch is tested for purity. You can check our shop for available stock.
What is the difference between 4-AcO-MET and Psilocin?
While both are tryptamines that act on the 5-HT2A receptor, 4-AcO-MET has an N-methyl-N-ethyl group, whereas psilocin has an N,N-dimethyl group. This slight difference changes the potency and duration of the effects.
📌 Key Takeaways
- 4-AcO-MET is a prodrug of 4-HO-MET, offering psilocin-like effects with a unique profile.
- Dosage range: 5–40 mg (start low).
- Legal status varies: Check local laws before purchasing.
- Safety first: Test your substance, use harm reduction practices, and avoid mixing with other drugs.
- Chem14.com is your trusted source for high-quality 4-AcO-MET and other research chemicals.
📚 References & Further Reading
- 4-AcO-MET – Wikipedia
- 4-AcO-MET – PsychonautWiki
- 4-AcO-MET – Cayman Chemical)
- 4-AcO-DMT vs. Psilocybin – Shroomtown
- Toxicity of 4-AcO-DET and 4-HO-MET – PubMed
💬 Engage With Us! Have you tried 4-AcO-MET? Share your experiences or questions in the comments below! For more insights, explore our blog or contact our team.
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