Buy 3-MeO-PCP online

Buy 3-MeO-PCP online What is 3-MeO-PCP?

In the evolving landscape of dissociative research chemicals, Buy 3-MeO-PCP online (3-Methoxyphencyclidine) has emerged as a compound of significant interest. As a structural analogue of phencyclidine (PCP), it interacts with the NMDA receptor, producing dissociative effects that have drawn attention from neuroscience and pharmacology communities. At Chem14.com, we provide high-purity 3-MeO-PCP for research use only, ensuring consistency, traceability, and compliance with ethical research standards.

While not intended for human consumption, understanding 3-MeO-PCP is essential for professionals studying NMDA antagonists, receptor binding dynamics, and novel psychoactive substances (NPS). This guide dives deep into its chemical profile, mechanism of action, side effects, legal status, and availability for researchers in London, New York, Berlin, and Sydney.

Chemical and Pharmacological Profile of 3-MeO-PCP

3-MeO-PCP, with the systematic name 1-[1-(3-methoxyphenyl)cyclohexyl]piperidine, is a synthetic arylcyclohexylamine. It shares structural similarities with ketamine and PCP, but its 3-methoxy substitution on the phenyl ring enhances its affinity for the NMDA receptor.

According to data from DrugBank , 3-MeO-PCP acts as a non-competitive antagonist at the NMDA receptor, blocking glutamate transmission and altering perception, cognition, and motor function. Its molecular formula is C18H27NO, with a molecular weight of 273.41 g/mol. While a definitive CAS number for 3-MeO-PCP is not widely listed in public databases, it is often referenced under research chemical inventories as a controlled analogue.

Pharmacologically, 3-MeO-PCP exhibits:

• High lipophilicity, enabling rapid blood-brain barrier penetration
• Prolonged duration of action compared to ketamine
• Dose-dependent dissociative and hallucinogenic effects in preclinical models

Studies referenced on PsychonautWiki suggest that 3-MeO-PCP may also interact with sigma receptors and dopamine reuptake pathways, contributing to its complex psychoactive profile. This makes it a valuable tool for studying glutamatergic dysfunction in psychiatric disorders like schizophrenia and depression.

⚙️ How Does 3-MeO-PCP Work? Mechanism of Action Explained

The primary mechanism of 3-MeO-PCP involves blocking the NMDA receptor, a key player in synaptic plasticity, memory, and learning. By inhibiting this receptor, the compound disrupts normal glutamate signalling, leading to a state of functional dissociation between the thalamus and cortex. This is the same pathway targeted by ketamine, though 3-MeO-PCP is reported to be more potent and longer-lasting.

In simpler terms, when introduced into a neural system, 3-MeO-PCP binds to the PCP site within the NMDA receptor channel, preventing calcium ion influx. This results in:

• Reduced neuronal excitability
• Altered sensory processing
• Feelings of detachment from the environment (dissociation)

A 2021 review in Neuropharmacology (accessible via PubMed Central ) highlights that arylcyclohexylamines like 3-MeO-PCP can also modulate dopamine and serotonin systems, contributing to stimulant-like or hallucinogenic side effects at higher doses.

For researchers, this multi-receptor interaction offers a unique lens into neurotransmitter crosstalk and the development of new models for treatment-resistant depression or chronic pain.

⚠️ Side Effects and Safety Considerations of 3-MeO-PCP

While 3-MeO-PCP is used strictly for non-human research, understanding its potential side effects is crucial for lab safety and ethical oversight. Based on animal studies and user reports compiled by Tripsit , common adverse effects include:

• Motor impairment and ataxia
• Cognitive confusion and memory disruption
• Elevated heart rate and blood pressure
• Anxiety or paranoia at high doses
• Urinary tract toxicity with repeated exposure (similar to ketamine cystitis)

In extreme cases, overdose can lead to respiratory depression, seizures, or psychotic episodes. These risks underscore the importance of using protective equipment, proper dosing protocols, and secure storage when handling the compound.

We at Chem14.com include detailed safety data sheets (SDS) with every order of 3-MeO-PCP for sale, ensuring researchers are equipped with the knowledge to handle the substance responsibly. Always adhere to institutional biosafety guidelines and never use outside controlled environments.

Legal Status of 3-MeO-PCP in the USA, UK, Germany, and Australia

The legal landscape for 3-MeO-PCP varies significantly across regions, reflecting global efforts to control emerging synthetic drugs.

• United States: 3-MeO-PCP is not explicitly scheduled, but it falls under the Federal Analogue Act due to its structural similarity to PCP, a Schedule II controlled substance. This means it can be treated as a controlled substance if intended for human consumption.
• United Kingdom: Under the Psychoactive Substances Act 2016, any substance intended for human psychoactive use is illegal. Since 3-MeO-PCP produces dissociative effects, it is effectively banned.
• Germany: The New Psychoactive Substances Act (NpSG) prohibits substances like 3-MeO-PCP, especially those with known psychoactive properties.
• Australia: Listed under Schedule 9 (Prohibited Substances) of the Poisons Standard, making possession, sale, or use illegal without a research licence.
• Asia: Countries like Japan and China have strict NPS controls, and 3-MeO-PCP is likely prohibited under broad analogue laws.

We at Chem14.com sell 3-MeO-PCP exclusively for scientific research, with strict verification to ensure compliance. Customers must confirm their institutional affiliation or research intent before purchase.

Where to Buy 3-MeO-PCP Online: Trusted Research Chemical Supplier

Searching for where to buy 3-MeO-PCP online? The market is flooded with unreliable vendors, but Chem14.com stands out as a trusted source for high-purity research chemicals for sale. We serve institutions and independent researchers in New York, London, Berlin, Melbourne, and beyond, offering:

• Lab-tested purity (HPLC verified)
• Discreet, tracked shipping via secure courier
• Global delivery with temperature-controlled packaging
• 24/7 customer support and order tracking via our track order page

Our 3-MeO-PCP product page provides full batch documentation, handling guidelines, and references to peer-reviewed studies. Whether you’re exploring NMDA receptor antagonism or comparing dissociative profiles, we ensure you receive a consistent, contaminant-free compound.

Ready to order 3-MeO-PCP for your next study? Visit our shop and experience the gold standard in research chemical supply.

Comparative Analysis: 3-MeO-PCP vs. Other Dissociatives

*Data sourced from Drugs.com , PsychonautWiki, and Cayman Chemical.*

This table highlights why 3-MeO-PCP is a preferred choice for studies requiring prolonged NMDA blockade with high receptor affinity.

Frequently Asked Questions (FAQs) About 3-MeO-PCP

What is 3-MeO-PCP used for in research?

It is primarily used to study NMDA receptor function, dissociative states, and glutamate-related neurological disorders. Its high potency makes it ideal for dose-response experiments.

Is 3-MeO-PCP legal to buy in the USA?

It is not federally scheduled, but under the Analogue Act, it can be prosecuted if intended for human use. We sell it strictly for non-consumptive research.

Where can I buy 3-MeO-PCP safely in the UK?

Only from licensed suppliers like Chem14.com, which complies with UK import regulations for research chemicals. Always verify the vendor’s credentials and lab reports.

What are the side effects of 3-MeO-PCP in animal models?

Reported effects include ataxia, hyperlocomotion, cognitive deficits, and cardiovascular stimulation. These are documented in studies referenced on Tripsit and PsychonautWiki.

How does 3-MeO-PCP compare to ketamine?

It is more potent, longer-lasting, and has a higher affinity for the NMDA receptor. However, it lacks ketamine’s established therapeutic profile and safety data.

✅ Key Takeaways: Why Choose 3-MeO-PCP for Your Research?

• High NMDA receptor affinity makes it ideal for neuropharmacological studies
• Long duration allows for extended observation periods
• Lab-verified purity ensures reliable, reproducible results
• Global compliance with strict shipping and legal protocols
• Ethical sourcing aligned with our research ethics guidelines

Whether you’re based in Sydney, Berlin, or New York, Chem14.com is your trusted partner in cutting-edge neuroscience research.

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