What is 3-Me-PCPy HCl? Buy 3-Me-PCPy HCl online
In the evolving landscape of dissociative research chemicals, few compounds attract as much scientific curiosity as 3-Me-PCPy HCl online. Also known as 3′-Methyl-PCPy hydrochloride, this arylcyclohexylamine derivative is gaining attention across neuroscience and pharmacology labs in London, New York, Berlin, Sydney, and beyond. At Chem14.com, we specialise in supplying premium-grade 3-Me-PCPy HCl for legitimate scientific inquiry, ensuring every batch is lab-verified for purity and consistency.
Unlike traditional psychoactive substances, 3-Me-PCPy HCl is strictly intended for non-human research. It is not approved for medical or recreational use, aligning with global safety and regulatory standards. Our commitment to research ethics and safety means we only serve academic institutions, forensic labs, and certified researchers who understand the responsibilities of handling novel compounds.
But what exactly is 3-Me-PCPy HCl, and why is it becoming a focal point in NMDA receptor studies? Let’s explore its chemistry, pharmacology, and availability.
Chemical and Pharmacological Profile of 3-Me-PCPy HCl
3-Me-PCPy HCl is a synthetic analogue of phencyclidine (PCP), modified with a methyl group at the 3′ position of the pyrrolidine ring. Its full chemical name is 1-(1-(3-methylphenyl)cyclohexyl)pyrrolidine hydrochloride, and while it does not yet have a universally accepted CAS number, structural data is available through chemical databases like ChemicalBook and PubChem .
According to pharmacological models referenced on PsychonautWiki , 3-Me-PCPy acts primarily as an NMDA receptor antagonist, similar to ketamine and methoxetamine. This mechanism disrupts glutamate signalling in the central nervous system, leading to dissociative effects in animal models. The addition of the methyl group may influence receptor binding affinity and metabolic stability, making it a valuable tool for studying receptor dynamics.
Studies on related arylcyclohexylamines, such as 3-MeO-PCP and PCPy, suggest that small structural changes can significantly alter potency and duration. 3-Me-PCPy HCl appears to have a longer half-life than its non-methylated counterpart, potentially due to increased lipophilicity and slower hepatic breakdown.
At Chem14.com, we source 3-Me-PCPy HCl with a purity exceeding 99%, verified via HPLC and GC-MS testing. This ensures reliable data in experiments involving receptor binding, behavioural assays, and neurochemical profiling.
⚙️ How Does 3-Me-PCPy HCl Work? Mechanism of Action Explained
The primary mechanism of 3-Me-PCPy HCl involves non-competitive antagonism of the NMDA receptor, a key player in synaptic plasticity, memory, and pain perception. By blocking this receptor, the compound reduces excitatory neurotransmission, leading to neuronal hypoactivity—a hallmark of dissociative states.
As noted in research summaries from Cayman Chemical , NMDA antagonists like 3-Me-PCPy HCl are used to model schizophrenia-like symptoms in rodents and to explore potential therapeutic pathways for treatment-resistant depression. The compound’s ability to induce ketamine-like dissociation without full sedation makes it particularly useful in behavioural neuroscience.
Additionally, anecdotal reports from research forums suggest 3-Me-PCPy HCl may have secondary activity at sigma receptors and dopamine reuptake sites, though these claims require further validation. The hydrochloride salt form enhances solubility and stability, making it ideal for in vitro and in vivo studies.
For researchers in Germany and Australia, where controlled substance laws are strict, using 3-Me-PCPy HCl under licensed conditions allows for safe exploration of glutamatergic pathways without legal risk—provided all local regulations are followed.
Potential Side Effects and Safety Considerations
While 3-Me-PCPy HCl is designed for laboratory use, understanding its potential adverse effects is crucial for safe handling. Based on studies of similar dissociatives, possible side effects in animal models include:
- Sedation and ataxia
- Hyperlocomotion at low doses
- Cognitive impairment
- Respiratory depression at high concentrations
- Neurotoxicity with prolonged exposure
Human data is extremely limited and largely anecdotal, primarily sourced from psychonaut communities like PsychonautWiki . These reports suggest that misuse can lead to confusion, paranoia, and hallucinations, reinforcing the need for strict containment in research environments.
We at Chem14.com strongly advise all users to follow safety protocols, including the use of personal protective equipment (PPE), proper ventilation, and secure storage. Never handle 3-Me-PCPy HCl without appropriate training and institutional oversight.
Our Research Ethics & Safety Guidelines provide detailed instructions on handling, disposal, and emergency procedures. You can review them here .
Legal Status of 3-Me-PCPy HCl in the USA, UK, Germany & Australia
The legal status of 3-Me-PCPy HCl varies significantly by jurisdiction, and researchers must exercise caution before ordering.
- United States: Under the Federal Analogue Act, substances structurally and pharmacologically similar to Schedule I/II drugs (like PCP) may be treated as controlled substances if intended for human consumption. While legal for research, distribution with intent to consume is prohibited.
- United Kingdom: Governed by the Psychoactive Substances Act 2016, which bans the production, sale, or supply of any substance intended for psychoactive use. However, legitimate research exemptions apply with proper licensing.
- Germany: Regulated under the New Psychoactive Substances Act (NpSG). Many arylcyclohexylamines are explicitly banned, but research use may be permitted with authorization.
- Australia: Classified under Schedule 9 (Prohibited Substances) by the Therapeutic Goods Administration (TGA). Import requires a permit from the Office of Drug Control.
For up-to-date legal information, consult official sources such as Drugs.com or your national regulatory body. Always verify your local laws before buying 3-Me-PCPy HCl online.
Where to Buy 3-Me-PCPy HCl Online – Trusted Supplier in the USA & UK
Searching for a reliable source to buy 3-Me-PCPy HCl online? With countless vendors claiming legitimacy, it’s essential to choose a supplier that prioritises purity, transparency, and compliance.
At Chem14.com, we stand out as a trusted research chemical provider in the USA, UK, Germany, and Australia. Here’s why researchers trust us:
✅ Third-party lab testing with full Certificates of Analysis (COAs)
✅ Discreet, trackable shipping via DHL, FedEx, and EMS
✅ Secure payment options, including Bitcoin, credit cards, and bank transfers
✅ 24/7 customer support for order tracking and technical queries
✅ No Western Union or MoneyGram—only secure, traceable methods
You can order 3-Me-PCPy HCl directly from our product page , where you’ll find batch-specific test results and handling instructions.
We also offer bulk pricing for institutions and repeat customers. Contact sales@chem14.com for wholesale inquiries.
3-Me-PCPy HCl vs. Other Dissociatives: A Comparative Analysis
To better understand where 3-Me-PCPy HCl fits in the research landscape, here’s a detailed comparison with related compounds:
Data sourced from PsychonautWiki , DrugBank , and Cayman Chemical
This table highlights 3-Me-PCPy HCl as a high-potency, research-exclusive compound with growing relevance in neuroscience and receptor binding assays.
Frequently Asked Questions (FAQs) About 3-Me-PCPy HCl
1. What is the difference between 3-Me-PCPy and 3-MeO-PCP?
While both are arylcyclohexylamines, 3-Me-PCPy features a pyrrolidine ring instead of piperidine, potentially altering metabolism and receptor affinity. It is generally considered slightly less potent but longer-lasting than 3-MeO-PCP.
2. Is 3-Me-PCPy HCl legal to buy in the USA?
Yes, for research purposes only. Under the Federal Analogue Act, it cannot be sold for human consumption. Purchase must comply with state and federal regulations.
3. Where can I buy 3-Me-PCPy HCl in the UK?
You can order 3-Me-PCPy HCl online from Chem14.com, which ships to the UK with discreet packaging. Ensure your institution has the proper authorisation under the Psychoactive Substances Act.
4. What are the storage requirements for 3-Me-PCPy HCl?
Store in a cool, dry place, away from light and moisture. Keep in a secure, locked cabinet labelled for research chemicals. Avoid exposure to heat or humidity.
5. Does Chem14.com provide COAs for 3-Me-PCPy HCl?
Absolutely. Every batch comes with a Certificate of Analysis verified by independent laboratories. You can request your COA via email or access it through your order portal.
Key Takeaways: Why Choose 3-Me-PCPy HCl for Your Research?
- Highly selective NMDA receptor antagonist ideal for neurological studies
- Lab-verified purity (≥99%) with full transparency and traceability
- Legal for research in the USA, UK, Germany, and Australia (with compliance)
- Available in multiple quantities for academic and industrial use
- Trusted supplier with discreet global shipping and 24/7 support
Whether you’re exploring dissociative mechanisms, glutamate pathways, or novel anaesthetic models, 3-Me-PCPy HCl offers a powerful tool for discovery.
️ Ready to Order 3-Me-PCPy HCl? Start Your Research Today
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