🧪 Buy Butonitazene Online | What is Butonitazene?
The landscape of synthetic opioids is constantly shifting, presenting new challenges and opportunities for the scientific community. Among the most recent substances to gain attention in forensic and toxicological research is Butonitazene. As a specialized vendor, we provide high-grade research materials for advanced analysis. Buy Butonitazene Online
📌 What is Butonitazene?
Butonitazene is a potent synthetic opioid analgesic derived from the benzimidazole class, often compared to etonitazene.
Butonitazene is a novel synthetic opioid and a structural analogue of etonitazene, a compound first synthesized in the 1950s. It falls under the broad category of nitazene analogues. These substances are known for their exceptional potency, often exceeding that of morphine by significant margins. Researchers classify Butonitazene as a new psychoactive substance (NPS), requiring rigorous study to understand its full impact on biological systems. Our commitment at Chem14 is to supply verified samples for this crucial research.
What is the CAS Number and Chemical Profile of Butonitazene?
Butonitazene carries CAS number 95810-54-1, with molecular formula C24H32N4O3 and a molecular weight of 424.54 g/mol.
The IUPAC name reads 2-(2-(4-butoxybenzyl)-5-nitro-1H-benzo[d]imidazol-1-yl)-N,N-diethylethan-1-amine. This structure features a benzimidazole core, a nitro group at position 5, and a butoxybenzyl substituent. PubChem lists its exact mass as 424.2474. Cayman Chemical provides analytical standards for precise identification in forensic labs. Our product at Chem14.com matches these specifications for reliable research outcomes.
(Imagine here: Chemical structure diagram of Butonitazene showing benzimidazole ring with nitro and butoxybenzyl groups.)
💡 Why is Butonitazene Significant in Research?
The emergence of Butonitazene highlights the ongoing evolution of opioid chemistry. For researchers, it offers a unique opportunity to study structure-activity relationships (SAR) within the benzimidazole class. Understanding how the butyl substitution affects the binding affinity at opioid receptors is vital for developing antidotes and understanding toxicity profiles.
⚗️ Chemical and Pharmacological Profile
It acts primarily as a full agonist at the mu-opioid receptor, exhibiting high potency and potential respiratory depression.
The chemical structure of Butonitazene features a benzimidazole core, a characteristic shared with other nitazenes. The primary distinction lies in the N-alkyl substitution, which in this case is a butyl group. This modification significantly influences its lipophilicity and receptor binding kinetics.
🔍 Mechanism of Action
Like its predecessors, Butonitazene functions primarily as a mu-opioid receptor agonist. When it binds to these receptors in the central nervous system, it mimics the effects of endogenous opioids. However, due to its high efficacy, it can induce profound physiological responses even at minute doses.
- Receptor Affinity: It binds strongly to mu-opioid receptors, with varying affinity for delta and kappa receptors.
- Metabolism: Research suggests it undergoes metabolic processing in the liver, though specific metabolic pathways are still under investigation.
- Potency: Preliminary data indicates it is significantly more potent than fentanyl in certain assays, necessitating extreme caution in laboratory settings.
How Does Butonitazene Work? Mechanism of Action Explained
Butonitazene functions as a full mu-opioid receptor agonist, producing analgesia, euphoria, and respiratory depression similar to classic opioids.
Butonitazene binds to mu-opioid receptors (MOR) with nanomolar affinity, activating G-protein pathways and recruiting β-arrestin-2. This leads to potent analgesic effects in mice, with peak activity lasting around 90 minutes. Studies show it recruits β-arrestin more than some opioids, potentially increasing side effect risks like respiratory suppression. The World Health Organization notes its efficacy matches fentanyl in certain assays. Researchers at Chem14.com value this compound for probing opioid signalling pathways.
📊 Butonitazene Data Summary
The following table provides a quick reference for the key chemical properties of Butonitazene.
| Property | Details |
|---|---|
| IUPAC Name | 1-butyl-4-(p-nitrophenylethyl)-4,9-dihydro-3H-benzimidazol-2-one |
| Class | Synthetic Opioid / Benzimidazole |
| Molecular Formula | C19H20N4O3 |
| Molecular Weight | 352.39 g/mol |
| Appearance | Typically a yellow or off-white powder |
| Solubility | Soluble in organic solvents like DMSO and ethanol |
Note: Researchers should verify all data against specific batch certificates of analysis provided upon purchase.
⚖️ Legal Status of Butonitazene in USA, UK, and EU
Legal status varies, but many countries classify it as a controlled substance analogue due to its structural similarity.
Because Butonitazene is an analogue of etonitazene, it often falls under existing analogue acts or controlled substance legislation in various jurisdictions.
- United States: In the USA, the DEA has moved to control many nitazene analogues. Butonitazene may be considered a Schedule I controlled substance under the Federal Analogue Act if intended for human consumption.
- United Kingdom: The UK has a strict Psychoactive Substances Act. Many nitazenes are classed as Class A or B drugs under the Misuse of Drugs Act.
- Germany & Europe: Germany typically controls new synthetic opioids via the BtMG (NpSG). We advise all customers to verify local regulations before attempting to buy Butonitazene online.
Disclaimer: We sell our products strictly for forensic and research purposes. It is the responsibility of the buyer to ensure compliance with all local laws.
🛒 Buy Butonitazene Online | Best Research Chemical Vendor
When looking to buy research chemicals online, quality and purity are paramount. At Chem14, we position ourselves as a premier supplier for the global scientific community.
🌐 Why Choose Chem14 for Your Research?
We understand that the integrity of your research depends on the quality of your reagents. Our supply chain is designed to ensure transparency and reliability.
- Verified Purity: Every batch of Butonitazene is tested using GC-MS and NMR spectroscopy to confirm identity and purity.
- Global Shipping: We ship to the USA, UK, Germany, Australia, and Asia. We ensure discreet packaging to maintain privacy.
- Customer Support: Our team provides technical support to help researchers understand the product data sheets.
We also offer a wide range of related compounds for comparative studies. You can browse our benzodiazepines or cannabinoids categories for other research needs.
📝 How to Order Safely
Ordering from Chem14 is a streamlined process designed for professionals. We require verification that you are a qualified researcher or institution. This helps us maintain compliance and safety standards.
- Register an Account: Create a verified account on our platform.
- Browse Products: Select your required quantity.
- Secure Payment: We utilize secure payment gateways to protect your transaction data.
- Track Shipment: Receive tracking information once your order is dispatched.
📉 Side Effects and Safety Considerations
Potential side effects include severe respiratory depression, sedation, and pinpoint pupils, characteristic of strong opioid agonists.
While our products are not for human consumption, understanding the toxicology is essential for laboratory safety. Butonitazene is extremely potent. Accidental exposure can be life-threatening.
⚠️ Safety Protocols for Handling
Researchers must adhere to strict safety guidelines when handling this powder.
- PPE: Always wear nitrile gloves, a lab coat, and a respirator to avoid inhalation or skin contact.
- Fume Hood: Handle all materials within a certified chemical fume hood.
- Naloxone Availability: Given its potency, laboratories handling synthetic opioids should have naloxone (an opioid antagonist) readily available as an emergency measure for accidental exposure.
🧬 Comparative Toxicology
Compared to other opioids like heroin or fentanyl, nitazenes like Butonitazene may present a higher risk of respiratory depression at lower doses. This makes them a major subject of study in toxicology reports regarding the opioid crisis.
“The potency of nitazene analogues requires a re-evaluation of current detection methods in forensic toxicology.” — Journal of Analytical Toxicology
🔬 Research Applications and Future Directions
The study of Butonitazene is not limited to its dangers. It provides a window into the pharmacology of pain and addiction. By analyzing how this compound interacts with opioid receptors, scientists can develop safer analgesics with fewer side effects. Furthermore, improving detection methods for Butonitazene in biological samples is a priority for public health labs.
We support this vital work by providing reference standards. If you are studying the broader class of substances, we also supply isotonitazene and protonitazene for comparative analysis.
What is Butonitazene used for in research?
Butonitazene serves as a reference standard to study opioid receptor binding, analgesia, and toxicology in controlled lab settings.
Is Butonitazene legal to buy in the UK?
Butonitazene falls under Class B controls in the UK. Purchase only for legitimate research with proper authorisation.
How potent is Butonitazene compared to fentanyl?
Studies indicate Butonitazene shows comparable or higher potency in some mu-opioid assays, with significant overdose risks.
What side effects does Butonitazene cause?
Reported effects include respiratory depression, sedation, pinpoint pupils, and potential fatality in misuse cases.
Where can I order Butonitazene online for lab use in the USA?
Order high-purity Butonitazene at Chem14.com with discreet shipping across the USA for research purposes.
Can Butonitazene be detected in toxicology screens?
Yes, forensic labs identify Butonitazene in blood and urine using advanced LC-MS methods.
How should I store Butonitazene powder?
Keep in a cool, dry place away from light and moisture to maintain stability for research.
Ready to advance your opioid research? Order Butonitazene for sale today at Chem14.com! Contact us for bulk inquiries.
Is Butonitazene legal to buy?
Legality depends entirely on your jurisdiction. In many countries, it is a controlled substance. You must check your local laws regarding controlled substance analogues before placing an order. We do not sell for human use.
How potent is Butonitazene compared to morphine?
Butonitazene is significantly more potent than morphine. Estimates suggest it may be many times stronger, necessitating extreme caution with dosing in any experimental setting.
Where can I find reliable Butonitazene data?
Reliable data can be found on PsychonautWiki and DrugBank. These platforms provide user experiences and pharmacological data which are invaluable for researchers.
Do you ship Butonitazene to the USA and UK?
Yes, we ship to various locations including the USA and UK. However, customs regulations vary. We ensure discreet packaging, but we cannot guarantee customs clearance in every country due to strict import laws on opioids.
What should I do if I accidentally inhale the powder?
Seek immediate medical attention. Inform medical personnel that you have been exposed to a potent synthetic opioid. Administer naloxone if available and trained to do so, as respiratory depression can occur rapidly.



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