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🌵 What Is Mescaline? Buy Mescaline Online at Chem14.com
Mescaline is a naturally occurring psychedelic alkaloid (3,4,5-trimethoxyphenethylamine) found in peyote and San Pedro cacti. It produces hallucinations, euphoria, and spiritual insights via serotonin receptor activation.
At Chem14.com, we provide high-purity mescaline for research purposes. Many researchers seek to buy mescaline online due to its historical significance in psychedelic studies. This compound has fascinated scientists and indigenous communities for millennia.
Mescaline originates from cacti in the Americas. Peyote (Lophophora williamsii) and San Pedro (Echinopsis pachanoi) contain it in varying concentrations. Synthetic versions exist for precise experimentation.
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We recommend reviewing our how to order guide and research ethics guidelines.
🔬 What Is the CAS Number and Chemical Profile of Mescaline?
Mescaline is a naturally occurring psychedelic protoalkaloid found in certain cacti, such as peyote and San Pedro. It produces altered perception, vivid visuals, and profound introspection.
Mescaline (3,4,5-trimethoxyphenethylamine) acts as a serotonergic hallucinogen. It occurs in plants like Lophophora williamsii (peyote) and Echinopsis pachanoi (San Pedro). Indigenous groups in Mexico and South America have used it in ceremonies for thousands of years.
Mescaline has CAS number 54-04-6. Its chemical formula is C₁₁H₁₇NO₃, with a molecular weight of 211.26 g/mol. It is a substituted phenethylamine, structurally similar to amphetamines but with hallucinogenic properties.
The structure features a phenethylamine backbone with three methoxy groups at positions 3, 4, and 5 on the phenyl ring. This configuration contributes to its serotonergic activity.
Key Chemical Properties Table:
| Property | Details |
|---|---|
| IUPAC Name | 2-(3,4,5-trimethoxyphenyl)ethanamine |
| Molecular Formula | C₁₁H₁₇NO₃ |
| CAS Number | 54-04-6 |
| Molar Mass | 211.26 g/mol |
| Appearance | White crystals (pure form) |
| Solubility | Moderately soluble in water |
| Melting Point | 35-36 °C |
| Primary Source | Peyote, San Pedro cacti |
Data sourced from credible chemical databases like PubChem.
What Is the Mechanism of Action of Mescaline?
Mescaline functions as a partial agonist at serotonin 5-HT2A receptors, the key site for classic psychedelic effects. It also interacts with 5-HT2C receptors and shows lower affinity for adrenergic and dopaminergic systems.
This activation leads to altered perception in the prefrontal cortex. Unlike LSD, mescaline has lower potency, requiring higher doses (200-400 mg common).
Studies confirm its role in visual and introspective experiences. For details, see research on serotonergic psychedelics.
What Are the Effects and Dosage of Mescaline?
Common research doses range from 200-400 mg for full effects. Threshold starts at 50 mg, strong at 400-800 mg. Onset occurs in 45-90 minutes, lasting 8-14 hours.
Dosage Guidelines (research context):
- Threshold: 50 mg
- Light: 50-200 mg
- Common: 200-400 mg
- Strong: 400-800 mg
Start low for safety. Effects include enhanced colors, geometric patterns, and emotional depth.
What Are the Side Effects and Risks of Mescaline?
Common side effects include nausea, vomiting, increased heart rate, anxiety, and pupil dilation. Physical discomfort often occurs early.
Psychological risks involve bad trips, paranoia, or rare psychosis in vulnerable individuals. No known fatalities from overdose; low toxicity profile.
Long-term risks include hallucinogen persisting perception disorder (HPPD) in rare cases. Avoid if history of mental health issues.
Harm reduction is essential. Consult sources like PsychonautWiki for safety.
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What Is the Legal Status of Mescaline in USA, UK, Germany, Australia?
Mescaline is a Schedule I substance in the USA (high abuse potential, no accepted medical use), with religious exemptions for Native American Church.
In the UK, Class A for pure form; plants often legal. Germany lists it under Anlage I (scientific use only). Australia prohibits it (Schedule 9).
Laws vary; research local regulations. For updates, check official sources.
📊 Mescaline vs Other Psychedelics Comparison Table
| Compound | Potency | Duration | Primary Source | Visual Intensity | Body Load |
|---|---|---|---|---|---|
| Mescaline | Low | 8-14 hours | Cacti | Organic, natural | High |
| LSD | Very High | 8-12 hours | Synthetic | Intense, sharp | Low |
| Psilocybin | Medium | 4-6 hours | Mushrooms | Dream-like | Medium |
Mescaline offers a gentler, more grounded experience.
What is mescaline?
Mescaline is a psychedelic alkaloid from cacti like peyote, inducing hallucinations and introspection.
How long do mescaline effects last?
Typically 8-14 hours, with peak at 4-6 hours.
Is mescaline addictive?
No physical addiction; psychological dependence rare.
Can I buy mescaline online legally?
For research only; check laws in USA, UK, Germany, Australia. See Chem14.com FAQ.
What are common side effects of mescaline?
Nausea, increased heart rate, anxiety; manage with calm setting.
Key Takeaways
- Mescaline is a classic psychedelic with roots in indigenous traditions.
- Acts via 5-HT2A receptors for profound effects.
- Low toxicity but risks include nausea and psychological distress.
- Legal restrictions apply; research responsibly.
- Explore related products in our tryptamines or psychedelics categories.
What is mescaline made from?
Mescaline derives from cacti like peyote and San Pedro. Synthetic versions match natural structure.
How long does mescaline last?
Effects persist 8-14 hours, with peak at 4-6 hours.
Is mescaline addictive?
No evidence shows physical addiction. Tolerance builds quickly but reverses fast.
Can I buy mescaline legally in the UK?
Pure mescaline falls under Class A restrictions. Consult laws; we supply for research only.
What are common mescaline side effects?
Nausea, elevated heart rate, and anxiety occur most often. Stay hydrated.
Ready to explore? Order from Chem14.com today. Track your shipment via track order. Contact us for questions. Stay safe in research.
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References (embedded above):
- Wikipedia on Mescaline
- PubChem Mescaline
- PsychonautWiki Mescaline
- Tripsitter Mescaline Guide
- DrugBank (related context)



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