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Welcome to Chem14.com, your trusted partner in advanced biochemical research. We specialize in providing top tier research chemicals to scientists and institutions across the globe. Our commitment to quality and transparency makes us a leading supplier for those looking to buy Gidazepam online and other novel compounds.
In this detailed journal, we explore the chemical nuances, pharmacological profile, and research potential of Gidazepam. Whether you are in the United States, the United Kingdom, Germany, or Australia, our comprehensive guide ensures you have the necessary data to conduct your studies safely and effectively.
What is Gidazepam and Its Chemical Structure? ⚗️
Gidazepam is a thienotriazolodiazepine, a subclass of the benzodiazepine family. It was developed in the Soviet Union and has been a subject of scientific interest for several decades due to its distinct molecular structure.
Gidazepam is an atypical benzodiazepine prodrug developed in the Soviet Union that converts to its active metabolite desalkylgidazepam, providing selective anxiolytic effects with reduced sedation compared to classic benzodiazepines.
Gidazepam is a thienotriazolodiazepine derivative with potent anxiolytic effects, primarily used in neuroscience research.
This compound differs from classic benzodiazepines because it incorporates a thiophene ring fused with a triazole ring. This specific structure alters its binding affinity and metabolic pathway. Researchers often compare it to Bromazolam and Etizolam when studying structure activity relationships.
Chemical and Pharmacological Profile
Chemically known as 7-bromo-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one, Gidazepam interacts with the central nervous system. It is crucial to note that while it shares mechanisms with other benzodiazepines, its pharmacokinetics make it unique.
- CAS Number: 4357-90-6
- Formula: C16H12BrClN2OS
- Molecular Mass: 395.69 g/mol
At Chem14.com, we ensure that every batch of Gidazepam for sale meets strict analytical standards. Our products are ideal for forensic analysis and receptor binding studies.
How Does Gidazepam Work? Mechanism of Action 🔬
Understanding the mechanism of action is vital for researchers utilizing this compound. Like other agents in the benzodiazepines category, Gidazepam exerts its effects by modulating the GABA-A receptor.
It acts as a positive allosteric modulator of GABA-A receptors, increasing the efficacy of the neurotransmitter GABA.
By binding to a specific site on the GABA-A receptor complex, Gidazepam enhances the inhibitory effects of gamma-aminobutyric acid (GABA). This results in neuronal hyperpolarization and decreased excitability in the brain. Research suggests that Gidazepam has a metabolite, desalkylgidazepam, which may contribute significantly to its prolonged duration of action.
Scientists studying anxiolytic compounds often focus on this metabolic pathway to understand how structural changes impact half-life and potency.
Gidazepam functions as a prodrug whose active metabolite desalkylgidazepam potentiates GABA-A receptors and stimulates neurosteroid production via TSPO binding, resulting in anxiolytic benefits without strong hypnotic effects.
The metabolite binds to GABA-A sites and opens chloride channels, calming neuronal excitability. At the same time TSPO activation promotes allopregnanolone synthesis, adding an extra layer of anxiolytic support. This combination explains why effects build gradually over several hours rather than delivering an immediate hit.
Studies confirm the parent compound shows lower direct GABA affinity than traditional benzodiazepines, which is why researchers turn to it for selective models. We recommend laboratory protocols account for the 30-60 minute onset and 1-4 hour peak when designing experiments.
📋 Gidazepam Properties Comparison Table
| Compound | Onset Time | Duration | Primary Research Focus | Sedation Level | Half-Life |
|---|---|---|---|---|---|
| Gidazepam | 30-60 minutes | Long (20-80 hours) | Selective anxiolytic, TSPO | Low | ~87 hours |
| Alprazolam | 30-60 minutes | Short (6-27 hours) | Potent anxiety models | Moderate | 6-27 hours |
| Bromazepam | 60 minutes | Intermediate | Anxiety and withdrawal studies | Moderate | 8-9 hours |
| Diazepam | 15-60 minutes | Long (20-80 hours) | Broad GABA research | High | 20-80 hours |
| Diclazepam | 30-60 minutes | Long | Long-acting benzo comparisons | Moderate | 42 hours |
This table highlights why many labs pair Gidazepam with our buy diclazepam online or buy bromazolam online options for side-by-side analysis.
Where to Buy Gidazepam Online Safely 🛡️
Finding a reliable supplier is the most challenging aspect of chemical research. At Chem14.com, we have built our reputation on trust and product integrity. When you order Gidazepam from us, you are guaranteed a product that is free from harmful adulterants.
Why Choose Chem14.com?
We serve a diverse client base, including university laboratories and private researchers. Our logistics network ensures discreet and prompt delivery to major hubs like London, New York, and Berlin.
- Purity Assured: We provide certificates of analysis for all our research chemicals.
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For those interested in similar compounds, our inventory also includes Flualprazolam and Clonazolam.
Gidazepam vs. Other Benzodiazepines 📊
To better understand the unique position of Gidazepam in the research community, we compare it with other popular research chemicals. This comparison helps researchers select the appropriate agent for their specific in vitro studies.
| Feature | Gidazepam | Diclazepam | Flubromazolam |
|---|---|---|---|
| Class | Thienotriazolodiazepine | Benzodiazepine | Benzodiazepine |
| Potency | Moderate | Low to Moderate | High |
| Duration | Long acting | Very Long acting | Long acting |
| Primary Use | Anxiolytic research | Sedation research | Hypnotic research |
| Metabolites | Active metabolites | Active metabolites | Active metabolites |
This table highlights why many researchers look to buy Gidazepam online when studying moderate potency, long duration agents. It offers a distinct pharmacological profile compared to the high potency of Flubromazolam.
What Are the Side Effects of Gidazepam? ⚠️
While our focus is on providing chemicals for research, understanding the biological effects is necessary for safety protocols. In clinical and anecdotal reports, often found on platforms like PsychonautWiki, Gidazepam exhibits side effects typical of the benzodiazepine class.
Potential side effects include drowsiness, sedation, muscle relaxation, and ataxia, typical of GABAergic modulation.
Researchers handling this compound must adhere to strict safety guidelines. Proper personal protective equipment (PPE) is mandatory to prevent accidental exposure. The sedative properties mean it can significantly impair motor function and cognitive ability if mishandled.
We strongly advise consulting our research ethics and safety guidelines before commencing any work with this substance.
Is Gidazepam Legal in the UK, USA, and Europe? 🌍
The legal status of research chemicals is complex and constantly evolving. As a responsible vendor, we stay updated on global regulations to ensure our clients can operate within the law.
- United Kingdom: Many benzodiazepines are controlled under the Psychoactive Substances Act or the Misuse of Drugs Act. Researchers must verify the specific scheduling of Gidazepam.
- USA: In the United States, the Federal Analogue Act may apply to certain benzodiazepine derivatives intended for human consumption. However, compounds sold strictly for research purposes may have different stipulations. Always check local state laws.
- Germany & Europe: Regulations vary, with Germany having strict controls under the BtMG.
We encourage all customers to review the legal disclaimer on our website. When you buy research chemicals online, you assume the responsibility of ensuring compliance with your local laws. Information regarding legal status can also be cross referenced with sites like Drugs.com.
How to Order Gidazepam for Research Purposes 📦
Ordering from Chem14.com is a streamlined process designed for efficiency. We understand that time is a critical factor in research.
- Browse Our Catalog: Visit our benzodiazepines section to find Gidazepam and related compounds like Pyrazolam.
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What is Gidazepam used for in research?
It is primarily used to study GABA receptor interactions and to understand the pharmacokinetics of thienodiazepines.
How potent is Gidazepam compared to Diazepam?
Gidazepam is generally considered to have similar or slightly lower potency than Diazepam but with a longer half life due to active metabolites.
Can I buy Gidazepam in the USA?
Yes, you can order Gidazepam for research purposes from Chem14.com, but you must ensure it complies with federal and state regulations.
Is Gidazepam the same as Desalkylgidazepam?
No, Desalkylgidazepam is a metabolite of Gidazepam. Both are subjects of separate but related research studies.
Where is the best place to find Gidazepam for sale?
Chem14.com is a trusted vendor offering high purity Gidazepam and other research chemicals with verified quality standards.
What are the storage requirements for Gidazepam?
It should be stored in a cool, dry place away from direct light to maintain chemical stability and purity over time.
What is Gidazepam primarily used for in research?
Gidazepam serves as a selective anxiolytic model compound. Researchers study its metabolite’s GABA-A and TSPO interactions to understand reduced-sedation pathways.
How long do the effects of Gidazepam last in laboratory settings?
The active metabolite provides effects lasting 20-80 hours with a half-life around 87 hours, making it excellent for long-duration observation protocols.
Does Gidazepam cause strong sedation like other benzodiazepines?
No. Its atypical profile produces minimal hypnotic or fatigue effects, which is why many labs prefer it for daytime or extended studies.
Is it safe to buy Gidazepam online in the USA and UK?
Yes, when purchased from licensed research vendors like Chem14.com for laboratory use only. Always confirm your institution’s compliance requirements.
What makes Chem14.com the best place to order Gidazepam?
We deliver independently verified purity, same-day shipping, discreet packaging and dedicated support for researchers across the USA, UK, Germany and Australia.
Can Gidazepam be combined with other research chemicals?
Many laboratories compare it with our buy clonazolam online or buy etizolam powder for differential analysis. Consult your protocol.
What is the recommended storage for Gidazepam powder?
Store in a cool, dry place away from light in an airtight container. Full guidelines ship with every order from Chem14.com.
Our team at Chem14.com remains committed to supplying the highest quality research chemicals. Questions about Gidazepam or any product in our cannabinoids, dissociative or stimulants ranges? Contact us today and let us support your next breakthrough.
Gidazepam remains a fascinating subject in the field of psychopharmacology. Its unique structure and metabolic profile offer valuable insights for researchers. At Chem14.com, we are dedicated to supporting the scientific community by providing access to high quality Gidazepam for sale.
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References and Further Reading
To ensure the accuracy of our data, we review information from established chemical databases and scientific literature. We encourage our clients to review these sources for deeper understanding.
- Detailed chemical structures and properties can be found at DrugBank.
- For user reports and qualitative data, PsychonautWiki is a valuable resource.
- General pharmacological information is available at Drugs.com.
- Historical context and chemical synthesis data are often archived on Wikipedia.
- For purchasing reference standards, Cayman Chemical provides technical data sheets.
- Harm reduction and safety guides are available at Tripsitter.
Disclaimer: All products sold by Chem14.com are intended for laboratory and research purposes only. They are not for human consumption or veterinary use. Buyers must be over 18 years old and comply with all local laws and regulations.



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