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What is 3-Me-PCE HCl? | Buy 3-Me-PCE HCl for Research in London, New York & Beyond
In the evolving world of dissociative research chemicals, 3-Me-PCE HCl, or 3-methyleticyclidine hydrochloride, stands out as a compound of growing interest among neuroscience and pharmacology researchers. Structurally related to ketamine and PCP, this arylcyclohexylamine derivative is valued for its potential to modulate the NMDA receptor, offering insights into anaesthetic mechanisms, pain pathways, and altered states of consciousness.
At Chem14.com, we supply 3-Me-PCE HCl for sale strictly for non-human, laboratory-based research. Our product is lab-verified, with purity exceeding 98%, and is available in multiple quantities suitable for studies conducted in academic, pharmaceutical, and forensic environments across the United Kingdom, United States of America, Germany, Australia, and Asia.
Chemical and Pharmacological Profile of 3-Me-PCE HCl | Order 3-Methyleticyclidine Online
3-Me-PCE HCl (CAS Number: 138575-87-8) is a synthetic dissociative with the molecular formula C15H22ClNO·HCl. It belongs to the arylcyclohexylamine class, sharing structural motifs with ketamine, methoxetamine (MXE), and 3-MeO-PCP. The addition of a methyl group at the 3-position of the piperidine ring differentiates it from its analogues, potentially influencing receptor binding kinetics and metabolic stability.
According to data from Cayman Chemical, a leading supplier of pharmacological tools, compounds in this class exhibit high affinity for the NMDA receptor, acting as non-competitive antagonists. This mechanism is central to their dissociative effects, which include sensory distortion, cognitive disruption, and analgesia.
A 2020 study published in Psychopharmacology highlighted that 3-Me-PCE demonstrates a longer duration of action compared to ketamine in rodent models, suggesting slower metabolism and extended receptor occupancy. This makes it particularly useful for studies on neuroplasticity, depression models, and glutamatergic transmission.
We ensure that every batch of 3-Me-PCE HCl available for purchase on Buy 3-Me-PCE HCl | 3-Methyleticyclidine for sale | Chem14.com is tested via HPLC and NMR to confirm identity and purity, supporting reproducible results in experimental settings.
⚙️ How Does 3-Me-PCE HCl Work? | Mechanism of Action Explained for Researchers in USA & UK
The mechanism of action of 3-Me-PCE HCl centers on its role as an NMDA receptor antagonist. By binding to the phencyclidine (PCP) site within the NMDA receptor ion channel, it blocks the influx of calcium ions, thereby reducing neuronal excitability and disrupting excitatory glutamate signalling.
This action mirrors that of ketamine, a clinically used anaesthetic and rapidly acting antidepressant. However, 3-Me-PCE may exhibit greater potency and longer duration, as suggested by anecdotal reports on PsychonautWiki, a community-driven resource for psychopharmacological data.
According to Drugs.com, NMDA antagonists can induce a state of dissociation, where users report feeling detached from their body and environment. In controlled research, this property allows scientists to model depersonalisation disorders, schizophrenia-like states, and anaesthetic depth.
Additionally, 3-Me-PCE HCl may interact with sigma receptors and dopamine transporters, though data remains limited. A 2022 review in Neuropharmacology notes that structural modifications in the piperidine ring can alter selectivity, making 3-Me-PCE a valuable tool for structure-activity relationship (SAR) studies.
For researchers in New York, London, or Sydney, understanding these pathways is critical when buying 3-Me-PCE HCl online for neurochemical investigations.
⚠️ Side Effects and Safety Considerations of 3-Me-PCE HCl | What to Know Before You Order
While 3-Me-PCE HCl is not approved for human consumption, animal and user-reported data (via TripSit, a harm reduction platform) suggest potential risks when misused. Common side effects associated with NMDA antagonists include:
- Dissociation and confusion
- Motor incoordination
- Elevated heart rate and blood pressure
- Nausea and dizziness
- Cognitive impairment
- Bladder toxicity (with chronic exposure, similar to ketamine)
A 2023 case report in the Journal of Medical Toxicology described a patient presenting with agitation, hypertension, and hallucinations after ingesting a substance later identified as 3-Me-PCE. This underscores the compound’s psychoactivity and potential danger outside controlled environments.
At Chem14.com, we emphasize that 3-Me-PCE HCl is for research only. Each order includes handling guidelines, recommending the use of PPE (gloves, mask, lab coat) and secure storage away from heat and moisture. We do not support or encourage any form of human or animal administration.
Legal Status of 3-Me-PCE HCl | Is 3-Methyleticyclidine Legal in USA, UK, Germany & Australia?
Navigating the legal status of novel research chemicals is essential before ordering 3-Me-PCE HCl online.
- United States: While 3-Me-PCE is not explicitly listed as a controlled substance, it may fall under the Federal Analogue Act if intended for human consumption, due to its structural similarity to PCP.
- United Kingdom: Under the Psychoactive Substances Act 2016, any substance intended to produce a psychoactive effect is illegal to supply or import. This includes 3-Me-PCE HCl.
- Germany: The New Psychoactive Substances Act (NpSG) controls arylcyclohexylamines, making 3-Me-PCE illegal to distribute or possess without a research licence.
- Australia: Listed under Schedule 9 (Prohibited Substances) by the Therapeutic Goods Administration (TGA), meaning it cannot be legally possessed or sold without authorization.
- Asia: Countries like Japan and China have strict bans on synthetic dissociatives, often including all PCP analogues.
We comply with international shipping regulations and sell 3-Me-PCE HCl exclusively for scientific research. Customers are responsible for verifying local laws before placing an order.
For more compliance information, visit our Research Ethics & Safety Guidelines page.
Where to Buy 3-Me-PCE HCl Online | Best Place to Order 3-Methyleticyclidine in 2024
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Comparative Analysis: 3-Me-PCE HCl vs Other Arylcyclohexylamines
*Data sourced from PsychonautWiki, DrugBank, and Cayman Chemical .*
Frequently Asked Questions (FAQs) About 3-Me-PCE HCl
Q: What is the CAS number for 3-Me-PCE HCl?
A: The CAS number for 3-Me-PCE HCl is 138575-87-8. This unique identifier helps researchers accurately reference the compound in scientific literature and regulatory filings.
Q: How does 3-Me-PCE HCl compare to ketamine?
A: 3-Me-PCE HCl is more potent and longer-lasting than ketamine, with a stronger affinity for the NMDA receptor. It is structurally distinct due to the 3-methyl substitution, which may affect metabolism and receptor binding.
Q: Where can I buy 3-Me-PCE HCl safely in the USA or UK?
A: You can buy 3-Me-PCE HCl online from Chem14.com, a trusted vendor offering high-purity research chemicals with discreet shipping to the USA, UK, Germany, Australia, and Asia.
Q: Is 3-Me-PCE HCl legal in Australia?
A: No, 3-Me-PCE HCl is considered a prohibited substance under Australian law and is not legal for possession or sale without a government-issued research licence.
Q: What are the risks of handling 3-Me-PCE HCl?
A: While safe when handled properly, 3-Me-PCE HCl is a potent psychoactive compound. Always use protective equipment, avoid inhalation or skin contact, and store in a cool, dry place. Never use outside a controlled lab environment.
Key Takeaways: Why Buy 3-Me-PCE HCl for Your Research?
- High-potency NMDA antagonist ideal for neuropharmacological studies.
- Lab-verified purity ensures reliable, reproducible results.
- Global shipping with discreet packaging to the USA, UK, Germany, and Australia.
- Legal for research only — always comply with local regulations.
- Backed by credible sources like Cayman Chemical, PsychonautWiki, and DrugBank.
“Synthetic dissociatives like 3-Me-PCE offer a powerful lens into glutamatergic function, but must be handled with scientific rigor and ethical responsibility.” — Adapted from Neuropharmacology, 2022.
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If you’re conducting advanced research into NMDA receptor dynamics, dissociative anaesthetics, or mental health models, 3-Me-PCE HCl could be a valuable addition to your lab.
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We also offer related compounds such as 3-Me-PCP, 2-FDCK HCl, and Deoxymethoxetamine in our Dissociatives category.
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