Buy 2F-DCK HCl online What is 2F-DCK HCl (2-Fluorodeschloroketamine)?
Buy 2F-DCK HCl online: In the evolving landscape of dissociative research chemicals, one compound gaining attention among neuropharmacologists is 2F-DCK HCl, also known as 2-Fluorodeschloroketamine. This fluorinated analogue of ketamine is not intended for human consumption but serves as a critical tool in studying NMDA receptor antagonism, cognitive function, and potential therapeutic pathways for mood disorders. At Chem14.com, we provide lab-tested, high-purity 2F-DCK HCl for scientific investigation, ensuring reliability and compliance with research ethics.
But what exactly is 2F-DCK HCl, and why are researchers in London, New York, Berlin, and Sydney turning to this compound? Let’s explore its chemical profile, mechanism of action, side effect potential, legal status, and where to buy 2F-DCK HCl online safely and securely.
Chemical and Pharmacological Profile of 2F-DCK HCl
2F-DCK HCl belongs to the arylcyclohexylamine class, a group that includes well-known substances like ketamine, PCP, and methoxetamine (MXE). Its systematic name is 2-(2-fluorophenyl)-2-(methylamino)cyclohexanone hydrochloride, and it is structurally analogous to deschloroketamine (DCK), with a fluorine atom substituted at the ortho position of the phenyl ring.
While the CAS number for 2F-DCK HCl is not widely listed in public databases such as DrugBank or PubChem, its structure has been referenced in forensic and analytical chemistry literature due to its emergence in the new psychoactive substances (NPS) market. According to PsychonautWiki , 2F-DCK exhibits a higher lipophilicity than ketamine, potentially enhancing its blood-brain barrier penetration and altering its pharmacokinetic profile.
Key chemical properties include:
- Molecular Formula: C₁₄H₁₈FNO·HCl
- Appearance: White to off-white crystalline powder
- Solubility: Soluble in water and polar organic solvents
- Stability: Store in a cool, dry place, protected from light
This compound is typically used in in vitro and in vivo models to assess glutamatergic neurotransmission, offering insights into depression, chronic pain, and dissociative states.
⚙️ How Does 2F-DCK HCl Work? Mechanism of Action Explained
The primary mechanism of 2F-DCK HCl involves non-competitive antagonism of the NMDA receptor, similar to its parent compound, ketamine. By blocking this receptor, 2F-DCK disrupts excitatory glutamate signalling, leading to altered perception, dissociation, and potential neuroplastic changes.
According to research published via Cayman Chemical , NMDA antagonists like 2F-DCK may promote the release of brain-derived neurotrophic factor (BDNF), which plays a role in synaptic plasticity. This pathway is of particular interest in the study of treatment-resistant depression and neurodegenerative conditions.
Additionally, anecdotal reports from research forums suggest that 2F-DCK may have a smoother onset and reduced psychotomimetic effects compared to ketamine, although these observations remain unverified in peer-reviewed studies. Its fluorine substitution may influence receptor binding affinity and metabolic stability, making it a valuable subject for structure-activity relationship (SAR) studies.
⚠️ Side Effects and Safety Considerations of 2F-DCK HCl
While 2F-DCK HCl is not approved for medical or recreational use, understanding its potential adverse effects is crucial for laboratory safety. Based on structural similarities to other arylcyclohexylamines, possible side effects in animal models may include:
- Sedation and motor impairment
- Increased heart rate and blood pressure
- Cognitive disturbances
- Bladder toxicity with prolonged exposure (a known issue with chronic ketamine use)
- Respiratory depression at high doses
A 2023 report in the European Journal of Clinical Pharmacology highlighted the risks associated with unregulated ketamine analogues, noting that even minor structural modifications can significantly alter toxicity profiles and metabolite formation.
We strongly advise all researchers to handle 2F-DCK HCl with appropriate personal protective equipment (PPE), including gloves and lab coats, and to conduct experiments in controlled environments. Our products are tested for purity and come with full Certificates of Analysis (COAs) to ensure safety and accuracy in research settings.
Legal Status of 2F-DCK HCl in the USA, UK, Germany, Australia, and Asia
The legal landscape for 2F-DCK HCl varies significantly across regions, and researchers must remain vigilant about local regulations before ordering research chemicals online.
For up-to-date legal information, consult official sources such as Drugs.com or national health departments. At Chem14.com, we sell 2F-DCK HCl exclusively for scientific research, and we do not ship to countries where such compounds are explicitly banned.
Where to Buy 2F-DCK HCl Online? | Trusted Supplier in the USA & EU
Searching for a reliable source to buy 2F-DCK HCl online can be challenging, given the prevalence of counterfeit vendors and untested products. That’s where Chem14.com stands out as a trusted research chemical supplier in the USA, UK, Germany, and Australia.
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- 99%+ purity, verified by third-party HPLC and GC-MS testing
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Whether you’re based in New York, London, Berlin, or Melbourne, you can order 2F-DCK HCl with confidence, knowing you’re receiving a product that meets rigorous quality standards.
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Comparison Table: 2F-DCK HCl vs. Other Dissociative Research Chemicals
Data sourced from PsychonautWiki , DrugBank , and internal lab reports at Chem14.com.
❓ Frequently Asked Questions (FAQs) About 2F-DCK HCl
1. What is the difference between 2F-DCK and ketamine?
2F-DCK HCl is a fluorinated derivative of deschloroketamine, lacking the chlorine atom found in ketamine and featuring a fluorine substitution. This modification may alter its binding affinity, metabolism, and duration of action, making it useful for comparative pharmacological studies.
2. Is 2F-DCK HCl legal to buy in the UK?
While not explicitly listed, 2F-DCK HCl likely falls under the Psychoactive Substances Act 2016, which bans the production, sale, and supply of any substance intended for human psychoactive use. However, it can be purchased for legitimate research purposes with proper documentation.
3. How should I store 2F-DCK HCl?
Store in a cool, dry place, away from direct sunlight and moisture. Keep in an airtight container at room temperature or refrigerated for long-term stability.
4. Can I buy 2F-DCK HCl with Bitcoin?
Yes. At Chem14.com, we accept Bitcoin, Ethereum, credit cards, and bank transfers to ensure secure, anonymous transactions. Paying with cryptocurrency adds an extra layer of privacy for international researchers.
5. Where can I find lab reports for 2F-DCK HCl?
All our products come with Certificates of Analysis (COAs), which can be requested via email or viewed upon request. These reports confirm purity, identity, and absence of contaminants using HPLC and GC-MS methods.
Key Takeaways: Why Researchers Choose 2F-DCK HCl
- 2F-DCK HCl is a fluorinated ketamine analogue used in neuroscience research.
- It acts as an NMDA receptor antagonist, offering insights into depression, pain, and cognition.
- High lipophilicity may enhance brain penetration compared to ketamine.
- Not for human consumption; intended solely for laboratory use.
- Legally available for research in many countries, but local laws must be verified.
- Available in high purity from trusted suppliers like Chem14.com .
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If you’re conducting cutting-edge studies in neuropsychopharmacology, 2F-DCK HCl could be a valuable addition to your research toolkit. At Chem14.com, we’re committed to providing premium-quality, lab-verified compounds with global shipping and unmatched customer support.
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